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hapgen2

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End to end sim for secure GWAS and PGS benchmarking. Uses 1000G based genotypes, with synthetic T2D and BMI traits from the PGS catalog. Compares baseline, differential privacy, and federated learning results. Data and PGS files not in repo, fetch from IGSR and the PGS Catalog. R code with bash/Slurm, and built to run on an HPC cluster. WIP.

  • Updated Nov 10, 2025
  • R

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