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bridge-recombinase

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ahmedanees-m / pen-stack

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A verification and grounding layer for AI-driven genome writing. Foundation models and a grounded co-scientist agent propose edits; PEN-STACK checks each against validated tools, never a language model: where a write is safe and durable, which enzyme makes it, and where it goes off-target. Calibrated, provenance-tracked, pre-registered.

python machine-learning bioinformatics reproducible-research computational-biology open-science crispr artficial-intelligence genetic-engineering gene-therapy inverse-design genome-engineering agentic-ai safe-harbor genome-writing bridge-recombinase recombinase
  • Updated Aug 4, 2026
  • Python

ahmedanees-m / pen-compare

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Hierarchical certification framework (5-gate TrueWriterScore) for programmable genome editors, with sensitivity analysis, cross-pipeline triangulation, and a RAG Q&A layer over the PEN-STACK.

python machine-learning bioinformatics ruff genome-editing genetic-engineering pre-registration streamlit is110 rag-llm agentic-ai pen-stack bridge-recombinase certification-framework true-writer pen-compare molecular-pen writer-not-scissors bridge-rna
  • Updated Jul 16, 2026
  • Python

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