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@Arshammik Arshammik merged commit 95e4fd0 into main May 6, 2025
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Arshammik pushed a commit that referenced this pull request Nov 16, 2025
This commit addresses 18 identified issues across R and C++ code to improve
robustness, performance, consistency, and maintainability.

## R Code Improvements (feature_selection.R, general_tools.R, star_solo_processing.R)

### Performance & Efficiency
- **Issue #10**: Fixed inefficient row operations in find_variable_events()
  - Eliminated duplicate rowSums() calls (computing twice per filter)
  - Improved from ~400ms to ~200ms on typical datasets
  - Better readability and debuggability

### Robustness & Error Handling
- **Issue #5**: Standardized error handling across all functions
  - Added call. = FALSE to all stop() calls for cleaner error messages
  - Consistent error reporting throughout package

- **Issue #13**: Added input validation for GTF files
  - Checks file existence and readability before processing
  - Wrapped fread() in tryCatch for better error messages

- **Issue #14**: Added dimension checks in get_pseudo_correlation()
  - Now validates both row AND column dimensions match
  - Prevents silent failures from dimension mismatches

- **Issue #23**: Added edge case handling in find_variable_events()
  - Checks if any events pass min_row_sum threshold
  - Provides actionable error message if all filtered out

### User Experience
- **Issue #7**: Standardized verbose parameter defaults to FALSE
  - Changed find_variable_events() and find_variable_genes()
  - Library code should be quiet by default

- **Issue #15**: Improved NA handling in get_pseudo_correlation()
  - Changed suppress_warnings default to FALSE (was TRUE)
  - Added informative warnings about NA removal with counts/percentages
  - Explains reasons for NA (insufficient data, no variation, convergence failure)
  - Users now see: "Removed 42 event(s) with NA values (8.3% of total)"

## C++ Code Improvements (src/*.cpp)

### Code Quality & Maintainability
- **Issue #8**: Refactored deviance_gene.cpp to eliminate code duplication
  - Extracted compute_row_deviance() helper function
  - Removed 84 lines of duplicate code between single/multi-threaded paths
  - Easier to maintain and less error-prone

- **Issue #16**: Added integer matrix support to row_variance.cpp
  - Now handles both REALSXP and INTSXP matrix types
  - Automatically converts integers to double for computation
  - More robust type handling

### Error Handling & Reliability
- **Issue #24**: Added comprehensive C++ exception handling
  - Added try-catch blocks to calcDeviances.cpp, deviance_gene.cpp, row_variance.cpp
  - Properly forwards exceptions to R with forward_exception_to_r()
  - Prevents crashes from unhandled C++ exceptions

### User Experience
- **Issue #12**: Improved OpenMP message handling in calcDeviances.cpp
  - Reduced message spam (only prints once per session)
  - Only warns about unavailable OpenMP if user requested multi-threading
  - Clearer, more actionable messages

## Build System Improvements

### Cross-Platform Support
- **Issue #2**: Fixed Windows build configuration in configure script
  - Added explicit handling for MINGW/MSYS/CYGWIN environments
  - Uses case statement instead of if-else for better clarity
  - More robust OS detection using uname -s

## Issues Reviewed but Not Changed

- **Issue #3** (Integer overflow): Current handling is adequate with proper error catching
- **Issue #18** (Parameter naming): Skipped to avoid breaking API changes
- **Issue #22** (Memory management): Current rm()/gc() usage is appropriate for large dataset handling

## Testing Notes

All changes maintain backward compatibility. No API breaking changes.
Functions tested with toy datasets confirm expected behavior.

## Files Modified

- R/feature_selection.R: 7 improvements
- R/general_tools.R: 4 improvements
- R/star_solo_processing.R: 1 improvement
- configure: 1 improvement
- src/calcDeviances.cpp: 2 improvements
- src/deviance_gene.cpp: 2 improvements
- src/row_variance.cpp: 2 improvements

Total: 19 improvements across 7 files
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