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Tune repairModelLeaks branch with master - #47

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JonathanRob merged 28 commits into
repairModelLeaksfrom
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Oct 16, 2018
Merged

Tune repairModelLeaks branch with master#47
JonathanRob merged 28 commits into
repairModelLeaksfrom
master

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JonathanRob and others added 28 commits October 10, 2018 14:03
Two reactions (HMR_1572 and HMGCOAtx) were deleted in a previous model update, but after further investigation, it was found that there is not sufficient evidence/reason for their removal. This script will effectively undo their deletion, restoring all of their previous information into the model.
This update is implemented by running the script miscModelCurationScript_20181012.m.
- Reactions HMR_1572 and HMGCOAtx that were removed by miscModelCurationScript_20180921.m are seamless restored here with the original indexes
- 5 non-standard fields (e.g. rxnKEGGID) are removed
- This script is outdated and thus moved to `deprecated`.
Push to master for pre-release v0.4.2
Script moved to ComplementaryScripts/modelCuration/
Also updated some comments, and changed default output file extension from .txt to .tsv
The file writing feature is now available in a separate function, "writeRxnChanges".
Function takes the rxnChange structure generated from the docRxnChanges function, and exports it to a text (tsv) file.
Add curations for adding inner membrane compartment
This update is implemented by running the script curateMitochMembraneComp.m.
- 4 duplicated reactions related to the electron transport chain were removed and updated to rxnAssoc.mat
- 2 unused reactions were constrained as ub=lb=0
- 15 electrogenic proton-transporting rxns were constrained to prevent proton from [m] to [c]
- 1 rxn LPAMtm was reversed in reaction direction
- 58 electrogenic rxns involving proton transport between [m] and [c] were modified by replacing H+[c] with H+[i]
- All modifications were saved to curateMitochMembraneComp_rxnChanges.tsv for tracking the changes
Push to master for pre-release v0.5.0

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Removed problematic file miscModelCurationScript_new.m. This file was not being actively used/maintained anyway.

@JonathanRob
JonathanRob merged commit 88477d1 into repairModelLeaks Oct 16, 2018
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2 participants