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Update 2026-07

This plugin is no longer actively supported by Geneious Prime. The last version it was known to run with was Geneious Prime 2026.1. It may run with newer versions, but it will no longer receive maintenance updates.

Authors

Tobias Thierer

Summary

A Geneious plugin for detecting coiled-coil structures in protein sequences using Lupas (1991)'s algorithm.

Installation

Download the gplugin file from http://geneious.com/plugins and drag it into Geneious.

Geneious developers, see: https://sites.google.com/a/biomatters.com/dev/documentation/install-external-open-source-plugins

About

Compare your sequence to a database of known parallel two-stranded coiled-coils and derive a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, you can then calculate the probability that the sequence will adopt a coiled-coil conformation.

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