Biophysical Assay Data Analysis

A Python package for analyzing and visualizing Differential Scanning Fluorimetry (DSF) data.

Features

• data import from commonly biophysical instrument formats. Currently supported instruments are QuantStudio7 and Lightcycler 480.
• quick visualization for raw data and the signals first derivative
• convenient calculation of relevant features such as the melting temperature Tm (here: max first derivative)
• identification of atypical shapes of signals (e.g. empty wells, failed experiment)

Installation

From PyPI (Recommended)

The easiest way to install is via pip:

pip install bada

From Source

To install the latest development version:

1. Clone the repository:

   git clone https://github.com/username/biophysical-assay-data-analysis.git
   cd biophysical-assay-data-analysis

2. Create a virtual environment (optional but recommended) using e.g. uv

3. Install the package in development mode:

   pip install -e .

Usage

To get started with this package, please refer to the example Jupyter notebooks in the notebooks folder. These notebooks provide step-by-step guides for common workflows and demonstrate the key functionality of the package.

License

This project is licensed under the MIT License - see the LICENSE file for details.