Merge pull request #195 from wikipathways/pico_P-TEFb_complex

Pico PTEFb complex and Selectins
sorgerlab · Jun 11, 2023 · dd4e9c7 · dd4e9c7
2 parents 22d2a4c + 3972b00
commit dd4e9c7
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Showing 7 changed files with 43 additions and 9 deletions.
diff --git a/entities.csv b/entities.csv
@@ -626,6 +626,7 @@ PRKAC
 PRKAR
 PRKG
 PRMT
+PTEFb
 Propionyl_CoA_carboxylase
 Protease
 Proteasome
@@ -699,6 +700,7 @@ SMC1
 SMURF
 SNAI
 SOD
+Selectin
 Sodium_channels
 Sodium_voltage_gated_channel_alpha_subunits
 Sodium_voltage_gated_channel_beta_subunits

diff --git a/equivalences.csv b/equivalences.csv
@@ -562,6 +562,7 @@ HGNC_GROUP,1202,GRID
 HGNC_GROUP,1203,Sodium_voltage_gated_channel_alpha_subunits
 HGNC_GROUP,1204,Sodium_voltage_gated_channel_beta_subunits
 HGNC_GROUP,1253,SCAR
+HGNC_GROUP,1281,PTEFb
 HGNC_GROUP,1298,CLEC
 HGNC_GROUP,1302,Adenosine_deaminase_family
 HGNC_GROUP,1303,ADA

diff --git a/export/famplex.belns b/export/famplex.belns
@@ -2,8 +2,8 @@
 Keyword=FPLX
 NameString=FamPlex
 DomainString=Gene and Gene Products
-VersionString=20230610
-CreatedDateTime=2023-06-10T15:49:48
+VersionString=20230611
+CreatedDateTime=2023-06-11T12:59:16
 DescriptionString=FamPlex is a collection of resources for grounding biological entities from text and describing their hierarchical relationships.
 QueryValueURL=http://identifiers.org/fplx/
 
@@ -635,6 +635,7 @@ PRKAC|CGPR
 PRKAR|CGPR
 PRKG|CGPR
 PRMT|CGPR
+PTEFb|CGPR
 PTGER|CGPR
 PYG|CGPR
 Patched|CGPR
@@ -730,6 +731,7 @@ STK3_4|CGPR
 STT3|CGPR
 SWI_SNF|CGPR
 Sarcoglycan_complex|CGPR
+Selectin|CGPR
 Sodium_channels|CGPR
 Sodium_voltage_gated_channel_alpha_subunits|CGPR
 Sodium_voltage_gated_channel_beta_subunits|CGPR

diff --git a/export/famplex.obo b/export/famplex.obo
@@ -1,5 +1,5 @@
 format-version: 1.2
-date: 10:06:2023 15:49
+date: 11:06:2023 12:59
 
 [Term]
 id: FPLX:5_hydroxytryptamine_receptors_G_protein_coupled
@@ -2609,9 +2609,7 @@ inverse_is_a: HGNC:REG1B
 inverse_is_a: HGNC:REG3A
 inverse_is_a: HGNC:REG3G
 inverse_is_a: HGNC:REG4
-inverse_is_a: HGNC:SELE
-inverse_is_a: HGNC:SELL
-inverse_is_a: HGNC:SELP
+inverse_is_a: FPLX:Selectin
 inverse_is_a: HGNC:SFTPA1
 inverse_is_a: HGNC:SFTPA2
 inverse_is_a: HGNC:SFTPD
@@ -11359,6 +11357,18 @@ inverse_is_a: HGNC:PRMT7
 inverse_is_a: HGNC:PRMT8
 inverse_is_a: HGNC:PRMT9
 
+[Term]
+id: FPLX:PTEFb
+name: PTEFb
+xref: HGNC_GROUP:1281
+is_a: FPLX:root
+has_part: HGNC:CCNK
+has_part: HGNC:CDK9
+has_part: HGNC:CCNT1
+has_part: HGNC:CCNT2
+has_part: HGNC:HEXIM1
+has_part: HGNC:HEXIM2
+
 [Term]
 id: FPLX:Propionyl_CoA_carboxylase
 name: Propionyl-CoA-carboxylase
@@ -12933,6 +12943,14 @@ inverse_is_a: HGNC:SOD1
 inverse_is_a: HGNC:SOD2
 inverse_is_a: HGNC:SOD3
 
+[Term]
+id: FPLX:Selectin
+name: Selectin
+is_a: FPLX:CLEC
+inverse_is_a: HGNC:SELE
+inverse_is_a: HGNC:SELL
+inverse_is_a: HGNC:SELP
+
 [Term]
 id: FPLX:Sodium_channels
 name: Sodium-channels

diff --git a/export/famplex_groundings.tsv b/export/famplex_groundings.tsv
@@ -1979,6 +1979,7 @@ PRL-3	O75365	uniprot	Gene_or_gene_product
 PRMT	PRMT	fplx	Family
 PSK2	Q08217	uniprot	Gene_or_gene_product
 PTC	P18502	uniprot	Gene_or_gene_product
+PTEFb	PTEFb	fplx	Family
 PTEN	P60484	uniprot	Gene_or_gene_product
 PTGER	PTGER	fplx	Family
 PTP1B	P18031	uniprot	Gene_or_gene_product
@@ -2328,6 +2329,7 @@ Sarcoglycans	Sarcoglycan_complex	fplx	Family
 Scavenger receptor	SCAR	fplx	Family
 Scavenger receptors	SCAR	fplx	Family
 Se	CHEBI:27568	chebi	Simple_chemical
+Selectin	Selectin	fplx	Family
 Shc	SHC	fplx	Family
 Shc family	SHC	fplx	Family
 Shp2	Q06124	uniprot	Gene_or_gene_product

diff --git a/export/hgnc_symbol_map.csv b/export/hgnc_symbol_map.csv
@@ -1744,6 +1744,8 @@ HES7,15977
 HEXA,4878
 HEXB,4879
 HEXD,26307
+HEXIM1,24953
+HEXIM2,28591
 HGF,4893
 HIF1A,4910
 HIF3A,15825

diff --git a/relations.csv b/relations.csv
@@ -4354,9 +4354,7 @@ HGNC,REG1B,isa,FPLX,CLEC
 HGNC,REG3A,isa,FPLX,CLEC
 HGNC,REG3G,isa,FPLX,CLEC
 HGNC,REG4,isa,FPLX,CLEC
-HGNC,SELE,isa,FPLX,CLEC
-HGNC,SELL,isa,FPLX,CLEC
-HGNC,SELP,isa,FPLX,CLEC
+FPLX,Selectin,isa,FPLX,CLEC
 HGNC,SFTPA1,isa,FPLX,CLEC
 HGNC,SFTPA2,isa,FPLX,CLEC
 HGNC,SFTPD,isa,FPLX,CLEC
@@ -5275,3 +5273,12 @@ HGNC,ICAM2,isa,FPLX,ICAM
 HGNC,ICAM3,isa,FPLX,ICAM
 HGNC,ICAM4,isa,FPLX,ICAM
 HGNC,ICAM5,isa,FPLX,ICAM
+HGNC,CCNK,partof,FPLX,PTEFb
+HGNC,CDK9,partof,FPLX,PTEFb
+HGNC,CCNT1,partof,FPLX,PTEFb
+HGNC,CCNT2,partof,FPLX,PTEFb
+HGNC,HEXIM1,partof,FPLX,PTEFb
+HGNC,HEXIM2,partof,FPLX,PTEFb
+HGNC,SELE,isa,FPLX,Selectin
+HGNC,SELL,isa,FPLX,Selectin
+HGNC,SELP,isa,FPLX,Selectin