This repository contains analysis code for studying the effect of temperature stress on the life cycle of Plasmodium falciparum. We also used the Malaria Cell Atlas to map the development stages , and found one distinct state that was present only in the temperature-stress induced cells.
Website for Data Exploration: https://sjohri.shinyapps.io/synchronised_plasmodium_cell_atlas/
Citation for the Publication:
Rawat, M., Srivastava, A., Johri, S., Gupta, I., & Karmodiya, K. (2021). Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Stage Transition under Temperature Stress in Synchronized Plasmodium falciparum Cells. Microbiology Spectrum, 9(1), e00008-21.