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Description
The following code reproduces the error:
(echo "##fileformat=VCFv4.2"
echo -e "#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO\tFORMAT\tA\t2:A") | bgzip > A.vcf.gz
tabix -f A.vcf.gz
(echo "##fileformat=VCFv4.2"
echo -e "#CHROM\tPOS\tID\tREF\tALT\tQUAL\tFILTER\tINFO\tFORMAT\tA") | bgzip > B.vcf.gz
tabix -f B.vcf.gz
bcftools merge A.vcf.gz B.vcf.gz --force-samples
with error:
[E::bcf_hdr_add_sample_len] Duplicated sample name '2:A'
bcftools: vcfmerge.c:683: maux_init: Assertion `n_smpl==bcf_hdr_nsamples(args->out_hdr)' failed.
Aborted (core dumped)
My understanding is that the resolution of duplicate sample names is not clever enough to assign a new valid name all the time. It seems like bcftools merge --force-samples
is changing the ID of A
to 2:A
but this sample already exists in the VCF causing the renaming attempt to fail.
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