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rpact 4.2.0

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@fpahlke fpahlke released this 25 Mar 05:54
91b1231

New features

  • For the functions getSimulationMultiArmMeans(), getSimulationMultiArmRates(), and getSimulationMultiArmSurvival() it is now possible to specify a parameter doseLevels to define the dose levels for a linear or sigmoidEmax dose-response relationship (see feature request #63)
  • Added support for unequal variances between two groups in getSampleSizeMeans(), getPowerMeans(), and getSimulationMeans() functions, see enhancement #70
  • testPackage() produces a comprehensive installation qualification report in html and pdf format (see new vignette Installation Qualification of rpact)
  • setupPackageTests() sets up the package tests by downloading the test files and copying them to the rpact installation directory
  • saveOptions() saves the current rpact options to a configuration file
  • resetOptions() resets the rpact options to their default values
  • Argument conservative added to getSampleSizeRates() function, see enhancement #39
  • Enable futility boundaries in Boundaries p Values Scale plot plot (type = 3) using options("rpact.plot.show.futility.on.pvalue.scale" = TRUE) or argument showFutilityBounds = TRUE, see enhancement #79
  • Enable beta-spending in Error Spending plot (type = 4) using options("rpact.plot.show.beta.spent" = TRUE) or argument showBetaSpent = TRUE, see enhancement #80. Furthermore, options("rpact.plot.show.alpha.spent" = FALSE) or argument showAlphaSpent = FALSE can be used to show only beta-spending in the plot

Improvements, issues, and changes

  • Issue for calculation of confidence intervals when using the conditional Dunnett test design
    (getDesignConditionalDunnett()) in analysis tool is fixed.
  • The full set of unit tests for rpact is now stored in a private repository.
    Only members of the 'RPACT User Group' have access to the tests.
    For more information, please visit: rpact.org/iq and RPACT Connect
  • Usage of maxInformation improved (see enhancement #65)
  • Line breaks in the output of getObjectRCode() improved (see #81)
  • testPackage(): additional warning details will be added to the test report if warnings exist* Issue #61 fixed
  • Issue #68 fixed
  • Flexibility of function getPiecewiseSurvivalTime() improved
  • Simulation allows the case #events = #patients
  • Test coverage improved
  • Plot subtitles improved
  • Warning message added for extreme choice of informationRates, userAlphaSpending, and userBetaSpending
  • Minor improvements

Full Changelog: v4.1.0...v4.2.0