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HyperTRIBE

HyperTRIBE is a technique used for the identification of the targets of RNA binding proteins (RBP) in vivo. This is an improved version of a previously developed technique called TRIBE (Targets of RNA-binding proteins Identified By Editing).

Please get the code from GitHub or download from here: DOI

Detailed doumentation is available at: http://hypertribe.readthedocs.io/en/latest/

For more details please see:

  1. Xu, W., Rahman, R., Rosbash, M. Mechanistic Implications of Enhanced Editing by a HyperTRIBE RNA-binding protein. RNA 24, 173-182 (2018). doi:10.1261/rna.064691.117

  2. McMahon, A.C., Rahman, R., Jin, H., Shen, J.L., Fieldsend, A., Luo, W., Rosbash, M., TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins. Cell 165, 742-753 (2016). doi: 10.1016/j.cell.2016.03.007.