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Meta-analysis - merge samples with the same sample ID - backwards functionality #2978

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@justinshaffer

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@justinshaffer

Hello,

Background: I'm conducting a meta-analysis across eight preps in a single study. The sample information file contains data for 384 samples. Each prep has the same 384 samples. The sample IDs are the same across the sample information file and all of the prep information files. My understanding was that this was OK, as long as samples are only duplicated across preps rather than in a single one.

Problem: When adding the final Deblur tables from each of the eight preps into an analysis, and not clicking the check-box to 'Merge samples with the same name', the resultant merged table only includes 384 samples and metadata from a single prep (e.g., only a single value for run_prefix even though there should be eight). I was able to reproduce this problem several times. I then decided to check the box to 'Merge samples with the same name', and it kept the samples across preps separate resulting in the expected 3,072 samples, and the merged metadata.

Potential solution: The functionality of the check-box to 'Merge samples with the same name' appears to work opposite to as it states. Switching this would likely fix this issue.

Thanks in advance for any help on resolving this issue!

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