How about 'rb_io_set_nonblock'. I got a #<RuntimeError: rb_io_set_nonblock not implemented> ruby version: truffleruby 19.1.0, like ruby 2.6.2, GraalVM CE Native [x86_64-linux] _Originally posted by @wangyin-git in https://github.com/oracle/truffleruby/issues/1730#issuecomment-519807723_