Method of measuring desynchronization of diurnal rhythms and quantification of circadian/diurnal variability
Our method of measuring internal desynchronization of diurnal rhythms through fitting sinusoids (Cosinor method [1]) and an extension to quantify circadian/diurnal variability.
When using this code to measure rhythms, please cite our paper:
Carr O, Saunders KEA, Tsanas A, Bilderbeck AC, Palmius N, Geddes JR, Foster R, De Vos M, Goodwin GM. Desynchronization of Diurnal Rhythms in Bipolar Disorder and Borderline Personality Disorder. Translational Psychiatry [Internet]. In Press.
And to quantify diurnal variability, please cite our paper:
Carr O, Saunders KEA, Tsanas A, Bilderbeck AC, Palmius N, Geddes JR, Foster R, Goodwin GM, De Vos M. Variability in phase and amplitude of diurnal rhythms is related to variation of mood in bipolar and borderline personality disorder. Scientific Reports [Internet]. 2018 Jan 26;8(1).
To run all of the code, the script Example.m and two data recordings (Acceleration Example.csv and Heart Rate Example.csv) are provided.
This recreates: Figure 1, the measures in Table 1, and Figure 2 from [2]; and also all diurnal variability measures from [3].
Oliver Carr is affilated at the Institute of Biomedical Engineering, Department of Engineering Science, University of Oxford.
Released under the GNU General Public License v3
This program is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version.
This program is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details.
You should have received a copy of the GNU General Public License along with this program. If not, see http://www.gnu.org/licenses/.
When using this code, please cite [2] and [3].
[1]: Halberg, F., Tong, Y. L. & Johnson, E. A. Circadian System Phase–An Aspect of Temporal Morphology; Procedures and Illustrative Examples. 20–48 (Springer Berlin Heidelberg, Berlin, Heidelberg, 1967).
[2]: Carr O, Saunders KEA, Tsanas A, Bilderbeck AC, Palmius N, Geddes JR, Foster R, De Vos M, Goodwin GM. Desynchronization of Diurnal Rhythms in Bipolar Disorder and Borderline Personality Disorder. Translational Psychiatry [Internet]. In Press.
[3]: Carr O, Saunders KEA, Tsanas A, Bilderbeck AC, Palmius N, Geddes JR, Foster R, Goodwin GM, De Vos M. Variability in phase and amplitude of diurnal rhythms is related to variation of mood in bipolar and borderline personality disorder. Scientific Reports [Internet]. 2018 Jan 26;8(1).