Description
#439 raises the issue of cross-session scaling differences between T1w images, which introduces the possibility that T2w images may also need to be scaled, and not merely realigned to the T1w images.
Reading the recon-all
log for uh2/sub-s483, the T2 image is aligned using bbregister
, which is 6-dof by default.
It seems reasonable to do a 9-dof registration of T2w images, which would then be saved to derivatives/fmriprep/<subject>/anat/<subject>_T2w_preproc.nii.gz
(or should it be <subject>_T2w_space-T1w_preproc.nii.gz
?). This re-aligned T2 would also be passed to FreeSurfer.
Questions:
Does FLIRT work well with T2w->T1w coregistrations? bbregister
has a --t2
flag to indicate the expected contrast in the moving image; it's not clear from the docs how that should be done with FLIRT. Or should we go ahead and do bbregister --9
? Which would mean we need to wait until after the first white
surfaces are created (autorecon2
) to load the T2.
I'm inclined toward using FLIRT to align all of the structurals at the very beginning, because we run the risk of getting too complicated with the recon-all
pipeline.