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Read adapter (or base quality-dependent) pre-trimming #80

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@MaximilianStammnitz

@BenjaminWehnert1008 this has been on our list for some time: especially for amplicon data with constant 5' and 3' flanks around the mutated ORF – but also for read pairs with significant QC drop at the ends – it makes sense to ask users to specify these sequences for a consistent read pre-trimming.

There are different nf-core modules we could implement upstream, arguably trimgalore is the best choice since it connects directly from the FastQC outputs: https://nf-co.re/modules/trimgalore/

Activity

  1. added this to the 1.1.0 milestone on Oct 8, 2026
  2. changed the title [-]Read adapter trimming[/-] [+]Read adapter (or base quality-dependent) pre-trimming[/+] on Oct 8, 2026
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