Presonus StudioLive AR12c

[Spade013]

Works well with single player. I haven't tried it with multiplayer.
I have it plugged into Channel 2 on the mixer.
The settings also allow the game audio to come out of the mixer.

RS_ASIO.ini

[Config]
EnableWasapiOutputs=1
EnableWasapiInputs=0
EnableAsio=1

[Asio]
; available buffer size modes:
;    driver - respect buffer size setting set in the driver
;    host   - use a buffer size as close as possible as that requested by the host application
;    custom - use the buffer size specified in CustomBufferSize field
BufferSizeMode=driver
CustomBufferSize=

[Asio.Output]
Driver=
BaseChannel=0
AltBaseChannel=
EnableSoftwareEndpointVolumeControl=1
EnableSoftwareMasterVolumeControl=1
SoftwareMasterVolumePercent=100

[Asio.Input.0]
Driver=StudioLive AR ASIO
Channel=1
EnableSoftwareEndpointVolumeControl=1
EnableSoftwareMasterVolumeControl=1
SoftwareMasterVolumePercent=100

[Asio.Input.1]
Driver=
Channel=1
EnableSoftwareEndpointVolumeControl=1
EnableSoftwareMasterVolumeControl=1
SoftwareMasterVolumePercent=100

[Asio.Input.Mic]
Driver=
Channel=1
EnableSoftwareEndpointVolumeControl=1
EnableSoftwareMasterVolumeControl=1
SoftwareMasterVolumePercent=100

Rocksmith.ini

[Audio]
EnableMicrophone=1
ExclusiveMode=0
LatencyBuffer=1
ForceDefaultPlaybackDevice=1
ForceWDM=0
ForceDirectXSink=0
DumpAudioLog=0
MaxOutputBufferSize=0
RealToneCableOnly=0
Win32UltraLowLatencyMode=1
[Renderer.Win32]
ShowGamepadUI=0
ScreenWidth=2560
ScreenHeight=1440
Fullscreen=2
VisualQuality=2
RenderingWidth=0
RenderingHeight=0
EnablePostEffects=1
EnableShadows=1
EnableHighResScope=1
EnableDepthOfField=1
EnablePerPixelLighting=1
MsaaSamples=4
DisableBrowser=0
[Net]
UseProxy=1

Goodbye crappy Real Tone Cable! You will not be missed.

[mdias]

Thank you for the report!
Added to the list 👍