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A computational model of pancreatic alpha cell glucagon secretion, implementing metabolic (glucose, FFA) and signalling (cAMP) pathways.

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Double-Switch-Model

A computational model of pancreatic alpha cell glucagon secretion, implementing metabolic (glucose, FFA) and signalling (cAMP) pathways.

Prerequisites

Python scientific stack (numpy, scipy, matplotlib) and cython must be pre-installed.

Setup

Part of the model is written in Cython. Compile the file via the command:

python src/setup_secretion.py build_ext --inplace

Running the model

Run the model via the command

python model.py

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A computational model of pancreatic alpha cell glucagon secretion, implementing metabolic (glucose, FFA) and signalling (cAMP) pathways.

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