update HS to v0.4.15

julia/fitted.heta

@@ -1,33 +1,32 @@
-// FitResult by HetaSimulator, saved 2021-12-02 at 13:23:09
-// status: :FTOL_REACHED, OF count: 2880, OF value: 2583.9226500233467
-sigma_K = 0.2503973572794826;
-sigma_L = 0.3299590537911647;
-sigma_S = 0.26897331987446105;
-sigma_T = 0.35666696551134747;
-sigma_U = 0.2861534767586667;
-sigma_P = 0.30643250367322544;
-Kp_K_D = 51.43863493827208;
-Kp_R_D = 86.33056444157613;
-Kp_L_D = 27.771910219037615;
-Kp_S_D = 149.03623688721174;
-Kp_T_D = 75.23779455763257;
-Kp_U_D = 78.00791112521424;
-PS_K_061 = 0.0008933512183572662;
-PS_L_061 = 0.020462440322424235;
-PS_R_061 = 0.06242032233930859;
-PS_S_061 = 0.00228353487143537;
-PS_T_061 = 0.001239081885507436;
-PS_U_061 = 0.0001262235980261698;
-Q_T_g = 2.236267594187401;
-bto_K_m = 0.0548644935062159;
-bto_L_m = 0.04348610278873404;
-bto_S_m = 0.021490259101483406;
-bto_T_m = 0.0016792464939615439;
-bto_U_m = 0.008284293913282729;
-deg_resp = 1.8002844302782601;
-kel_L_D_m = 0.08726122494830593;
-koef_resp_K = 81.79696970171523;
-koef_resp_L = 148.45774478141843;
-koef_resp_R = 227.6917819513605;
-tar_S = 1.592752135402004;
-w_B_m = 0.29426031885243725;
+// FitResult by HetaSimulator, saved 2024-07-19 at 16:34:23
+// status: :FTOL_REACHED, OF count: 1309, OF value: 6410.72212318048
+sigma_K = 0.20000283953557862;
+sigma_L = 0.20722028061496323;
+sigma_S = 0.19096873192494565;
+sigma_T = 0.15869644824298307;
+sigma_U = 0.1264447990105922;
+sigma_P = 0.12638098603211556;
+Kp_K_D = 54.713497169861554;
+Kp_R_D = 93.07602756629771;
+Kp_L_D = 37.95679528406977;
+Kp_S_D = 151.38640367892714;
+Kp_T_D = 77.11482162082308;
+Kp_U_D = 84.31243578973493;
+PS_K_061 = 0.0009002235954859103;
+PS_L_061 = 0.023037806925879877;
+PS_R_061 = 0.059505249158106815;
+PS_S_061 = 0.0023324191427573906;
+PS_T_061 = 0.0012276566587157073;
+PS_U_061 = 0.00013114632098627847;
+Q_T_g = 2.4029483383901677;
+bto_K = 0.08820520884907626;
+bto_L = 0.12161102855684248;
+bto_S = 0.1383462297926806;
+bto_T = 0.010966647055907244;
+bto_U = 0.21196809365097563;
+deg_resp = 2.2822987314286247;
+kel_L_D = 3.5691060112431154;
+koef_resp_K = 112.15012300261401;
+koef_resp_L = 218.17608603011126;
+koef_resp_R = 286.3562085906377;
+w_B = 0.08310745645239273;

julia/run.jl

@@ -67,7 +67,7 @@ to_fit = [
     #:tar_S => 9.044673e-01,
     :w_B => 8.138074e-02
 ]
-# OFV: 2584 => 6410
+# OFV: 2584 => 6410 (v0.4.15)
 fit_res = fit(p, to_fit)
 
 optim(fit_res)

platform.json

@@ -1,5 +1,5 @@
 {
-  "builderVersion": "^0.7.4",
+  "builderVersion": "^0.8.5",
   "id": "drug-loaded-nanoparticles",
   "notes": "PBPK Modeling For Therapeutic Nanoparticles Loaded With Drug",
   "version": "v0.1.1",