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avoids the corner case where a gene that modified for outlier injection is set to 0 resulting in a gene that has no reads across all samples.
if samples A, B, C have 0 counts and sample D has 100 counts for
geneX
. IfgeneX
and sample D are modified to 0 to find outliers then in this new counts matrixgeneX
has no reads for all samples resulting in a failedcheckCountRequirements
check.There are other ways to avoid this corner case, but seems simplest.