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Assemble2: visualize, construct and study RNA architectures

Main features:

  • Assemble2 allows you to visualize and edit RNA structures described in a file (CT, BPSep, FASTA, PDB) or recovered from databases (RFAM, PDB, SSTRAND).
  • Assemble2 provides a panel dedicated to the dispaly and the interactive manipulation of an RNA secondary structure (2D).
  • if the 2D is derived from a solved 3D, Assemble2 can load this 3D into to the viewer UCSF Chimera.
  • Assemble2 keeps a link between the two structures, making the 2D a guide in the exploration of the solved 3D.
  • this link makes also the 2D a guide for the construction of a new 3D. Each selection in the 2D can be used to query a database of 3D fragments to be assembled into a 3D model.
  • Assemble2 is connected to RNA algorithms and databases made available as Web Services from a cloud in order to automate recurrent tasks of a working session:
    • 2D prediction from an RNA primary sequence
    • 2D annotation from an RNA tertiary structure
    • 2D plot of a secondary structure
    • query of 3D fragments from a 2D selection

Assemble2 has been developed with the Java language on MacOSX. It has been tested on MacOSX and Linux Ubuntu. But it should run on any operating system having a Java environment.

Assemble2 description

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Assemble2 allows you to design your RNA 2D structure interactively and to create and assemble the corresponding RNA 3D modules directly in UCSF Chimera

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