MultiB0_B1_qCEST_brain

Open MultiB0-MultiB1 CEST MRI dataset for comparing different quantification models

Methods

• Data acquisition: obtained from 1 healthy subject at two field strengths
• Scanners: MAGNETOM Prisma (3T) and Terra.X (7T)
• Pulse train preparation: conventional Spin-Lock pulse train preparation (10 pulses, DC = 50%, tp = 100 ms, td = 100 ms)
• B1 levels: 0.3, 0.6, 0.9, 1.5, 2, 2.7, 4 µT
• Offsets:
  • between -100 and 100 ppm
  • finer sampling between -6 and 6 ppm with a step of 0.25 ppm for B1 < 4 µT
  • step width for B1 = 4 µT was 0.5 ppm which was later interpolated
• Image readout: 3D snapshot-CEST GRE
• Mapping methods:
  • B1 and B0 maps measured using the WASABI method
  • Co-registration and reslicing 7T data onto 3T data
• Homogeneity criteria:
  • simultaneously homogenous B0 and B1 values for region-of-interest
  • Defined as:
    • ± 5 % deviation from B1 map
    • ± 0.1 ppm deviation from B0 map
• Regions of Interest (ROI):
• Grey and white matter regions within homogenous region

Data Description

NIfTI (.nii) Data

• This Git repository contains .nii files for each measured sequence at 3T and 7T
• The corresponding WASABI data (B0 and B1 maps) is provided as .mat file
• A mask for simultaneously homogenous B0 and B1 values is included as .nii file
• Segmentation data of grey and white matter regions is provided

EXCEL file with MultiB0_B1 data

The Spin Lock dataset for 3T and 7 T in grey and white matter is available in an Excel file

Sheets included:

• GM_7T: Grey matter data at 7T
• WM_7T: White matter data at 7T
• GM_3T: Grey matter data at 3T
• WM_3T: White matter data at 3T

Each sheet includes:

• Sequence setup
• Calculated T1 and T2 values
• Offsets
• Mean Z spectra for ROI in grey and white matter

All data provided in the Excel file ready to use as described here: https://cest-sources.org/doku.php?id=bm_sim_fit