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statgen-prerequisites

Notes on statistical background for statistical genetics practitioners

Table of Content

Section Subsection Topic
Basic Concepts Genotype Coding
Minor Allele Frequency
Hardy-Weinberg Equilibrium
Correlation Between variants Linkage Disequilibrium
Linkage Disequilibrium Score
Between individuals Genetic Relationship Matrix
Between variables Factor Analysis
Principal Component Analysis
Genetic Associations Basic model Ordinary Least Squares
Extend to binary outcome Odds Ratio
Extend to multiple variables Marginal vs. Joint Effects
Summary Statistics
Genetic effects Random Effect
Proportion of Variance Explained
Linear Mixed Model
Covariates Confounder
Collider
Mediator
Multiple studies Meta Analysis Fixed Effect
Meta Analysis Random Effect
Statistical Inference Likelihood and MLE Likelihood
Maximum Likelihood Estimation
LR and LRT Likelihood Ratio
Bayesian versus Frequentist Bayesian and Frequentist
Bayes Rule
Bayes Factor
P-value
Bayesian Model Bayesian Normal Mean Model
Bayesian Multivariate Normal Mean Model
Multiple Bayesian Models Bayesian Model Comparison
Bayesian Mixture Model

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Notes on the statistics background for statistical genetics practitioners

statfungen.github.io/statgen-prerequisites/

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