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Quantum Machine Learning for Non-Hodgkin Lymphoma Detection

Abstract

Non-Hodgkin Lymphoma (NHL) represents a significant portion of cancer cases worldwide, with traditional detection methods often lacking in early and precise diagnosis. Leveraging Quantum Machine Learning (QML), we introduce a pioneering approach for detecting NHL using histopathological images. Our methodology integrates a Convolutional Neural Network (CNN) for initial feature extraction, followed by a Quantum Convolutional Neural Network (QCNN) and a Quantum Neural Network (QNN) for enhanced detection capabilities. This novel approach aims to improve diagnostic accuracy and efficiency, potentially leading to better treatment outcomes and reduced healthcare costs.

Keywords

  • Non-Hodgkin Lymphoma
  • Quantum Machine Learning
  • Quantum Convolutional Neural Network
  • Quantum Neural Network
  • Histopathological Images

Objectives

  • Utilize CNN for initial feature extraction and QCNN for advanced feature representation.
  • Implement QNN for accurate NHL detection, comparing its efficacy against traditional methods.

Proposed Solution

Our solution follows a comprehensive workflow:

  1. Data Acquisition: Compile a dataset comprising histopathological images and patient records.
  2. Feature Extraction: Employ CNN for initial extraction, then enhance features with QCNN.
  3. Detection: Leverage a QNN for final detection, aiming for higher accuracy and efficiency.
  4. Patient Privacy: Ensure confidentiality through data de-identification techniques.

Impact and Innovation

By applying QML to NHL detection, we aim to enhance diagnostic processes significantly. This research could serve as a catalyst for broader advancements in precision medicine and early disease detection, potentially improving patient outcomes and reducing treatment costs.

Dataset

The project utilizes the PCam dataset for training the QML model, available here: PCam Dataset on Kaggle

Current Progress

We have achieved an initial accuracy of 85.56% in NHL detection using our quantum-enhanced system, marking a promising step towards revolutionizing cancer diagnostics.

License

MIT License

Copyright (c) 2024 Siddharth Bhetariya

Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions:

The above copyright notice and this permission notice shall be included in all copies or substantial portions of the Software.

THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE SOFTWARE.

This project is build during the Unisys Innovation Program Y-15

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