Heart disease is one of the leading causes of mortality worldwide. Early identification and prediction of heart disease using machine learning models can help in timely medical intervention. This guide provides a step-by-step approach to building a heart disease prediction model using machine learning.
We will use the Heart Disease UCI Dataset from Kaggle: 🔗 Dataset Link: Heart Disease UCI - Kaggle
The dataset contains 14 attributes used to predict the presence of heart disease. The key attributes include:
- Age: Age of the patient.
- Sex: Gender (1 = Male, 0 = Female).
- Chest Pain Type (cp):
- 0: Typical angina
- 1: Atypical angina
- 2: Non-anginal pain
- 3: Asymptomatic
- Resting Blood Pressure (trestbps): Blood pressure in mm Hg.
- Cholesterol (chol): Serum cholesterol level.
- Fasting Blood Sugar (fbs): (1 = True, 0 = False).
- Resting ECG (restecg): ECG results (0 = Normal, 1 = ST-T wave abnormality, 2 = Left ventricular hypertrophy).
- Max Heart Rate (thalach): Maximum heart rate achieved.
- Exercise-Induced Angina (exang): (1 = Yes, 0 = No).
- ST Depression (oldpeak): ST depression induced by exercise.
- Slope of ST Segment (slope): (0 = Upsloping, 1 = Flat, 2 = Downsloping).
- Number of Major Vessels (ca): Count of major vessels (0-3).
- Thalassemia (thal): (0 = Normal, 1 = Fixed defect, 2 = Reversible defect).
- Target Variable: (1 = Presence of heart disease, 0 = No heart disease).
- Remove duplicate values (if any).
- Handle missing values using mean/median imputation for numerical features.
- Convert categorical features (e.g.,
cp
,thal
,slope
) into numerical values using One-Hot Encoding or Label Encoding.
- Standardize numerical features using Min-Max Scaling or Standardization (Z-score normalization).
- Use histograms to analyze age distribution.
- Plot correlation heatmaps to identify feature relationships.
- Use boxplots to detect outliers in
chol
,trestbps
, andthalach
.
- Target variable distribution: If imbalanced, apply SMOTE (Synthetic Minority Over-sampling Technique).
- 80% Training Set, 20% Testing Set for model evaluation.
- Use Stratified Sampling to maintain class balance.
Different ML models can be used for heart disease prediction:
- Logistic Regression (Baseline Model)
- Random Forest Classifier
- Support Vector Machine (SVM)
- Gradient Boosting (XGBoost, LightGBM)
- Artificial Neural Networks (ANNs)
- Fit selected models on training data.
- Optimize using hyperparameter tuning (GridSearchCV, RandomizedSearchCV).
Use the following metrics for evaluating model accuracy:
- Accuracy:
(TP + TN) / (TP + TN + FP + FN)
- Precision, Recall, and F1-score to measure class performance.
- ROC-AUC Curve for model discrimination ability.
- Confusion Matrix for analyzing false positives & false negatives.
- Evaluate multiple models and select the best based on precision-recall balance.
- If Random Forest/XGBoost performs better, use Feature Importance Analysis to interpret key predictors.
- Save the final model using Pickle (.pkl) or Joblib.
- Use Flask/FastAPI to create an API endpoint for real-time predictions.
- Deploy on AWS, Google Cloud, or Heroku.
- Monitor Model Performance: Use new data updates for retraining.
- Explainability & Interpretability: Use SHAP (SHapley Additive Explanations) to understand feature importance.
- Enhance Performance: Try deep learning models (ANN, CNN for ECG analysis).
Building a Heart Disease Prediction System using Machine Learning enables early detection and better decision-making in healthcare. By following these steps, we can create a robust, scalable model for real-world medical applications.
🔗 Dataset: Heart Disease UCI - Kaggle
🚀 Next Steps: Enhance the model using Deep Learning (CNN/LSTM for ECG data).