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Update overview.rst #47

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2 changes: 1 addition & 1 deletion docs/overview.rst
Original file line number Diff line number Diff line change
Expand Up @@ -37,7 +37,7 @@ Given the remarkable success of Convolutional Neural Network (CNN) in retrieving
CNN architectures have been developed to learn interaction patterns in PPI interfaces [2]_, [3]_.

CNNs however come with major limitations: First, they are sensitive to the input PPI
orientation, and it may require data augmentation (i.e. multiple rotations of the input data) for the
orientation, which may require data augmentation (i.e. multiple rotations of the input data) for the
network to forget about the orientation in the learning process; second, the size of the 3D grid is
unique for all input data, which does not reflect the variety in interface sizes observed in experimental
structures and may be problematic for large interfaces that do not fit inside the predefined grid size.
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