HI! I am glad to see you in my profile! You are welcome🐅

ARIUNA AIUSHEEVA

+79138700781

aryuna.ayusheeva.1998@mail.ru

EDUCATION

Bioinformatics Institute

Bioinformatics for biologists 2023 – 2024

Siberian State Medical University

Department of Medical Biology, medical cybernetics 2015 - 2021

Institute of Protein Research

PhD student in molecular biology, group of protein biosynthesis regulation 2021 - present

PROFESSIONAL EXPERIENCE

Institute of Protein Research RAS | 2021 - Present

• Working with chromatin accessibility data (ATAC-seq, DRIP-seq, CHIP-seq), identifying allele-specific binding of transcription factors to regulatory variants in U2OS cell line. My role is to develop the basic pipeline for variant calling

• Annotation and enrichment analysis of allele-specific transcription factor binding at SNPs. My role was to annotate the main significant SNPs found in the COVID19-hg GWAS meta-analysis

Central Scientific Research Laboratory of SSMU | 2020

Performing statistical analysis of clinical data Another project is dedicated to the relationship between biliary microbiota and bile acids composition in cholelithiasis. Preprocessing of 16S sequencing data and assessment of ecological metrics are performed

Summer School on Bioinformatics | 2019

RNA-seq data processing, studying how transcriptome changes as cells mature

Skills

Python

(pandas, sklearn, numpy, scipy ) (subprocess32, pybedtools, samtools)

C++, Qt5

bash (gnu parallel), Snakemake, git,

experienced with Rest API

R (ggplot2, corrplot, psych, plotROC,

lattice, tidyverse) mySQL

Ability to use bioinformatics programs

Qiime2, FastQC, Cutadapt, GATK, PICARD, Samtools

PUBLICATIONS

ANANASTRA

Alexandr Boytsov, Sergey Abramov, Ariuna Z Aiusheeva, Alexandra M Kasianova, Eugene Baulin, Ivan A Kuznetsov, Yurii S Aulchenko, Semyon Kolmykov, Ivan Yevshin, Fedor Kolpakov, Ilya E Vorontsov, Vsevolod J Makeev, Ivan V Kulakovskiy, ANANASTRA: annotation and enrichment analysis of allelespecific transcription factor binding at SNPs, Nucleic Acids Research, Volume 50, Issue W1, 5 July 2022, Pages W51–W56, https://doi.org/10.1093/nar/gkac262

Analysis of clinical data

Aiusheeva A.J., F.O. (2020). All-Russian final 79th student scientific conference named after. N.I. Pirogov. Analysis of clinical data for risk assessment in the development of associated pathologies for opisthorchiasis invasion in the Shegarsky district of Tomsk region(p. 193). Tomsk

CERTIFICATES

• Our team developed a game. NGSchool , 2021 (online)
• Future Biotech Winter Retreat 2020: Genomics 79th All-Russian Student Scientific Conference (dedicated to the memory of N.I. Pirogov), 2020, Tomsk
• Introduction to Bioinformatics: Metagenomics (by Coursera)
• Bioinformatics Summer School, July-August 2019, Moscow Institute of Physics and Technology, Moscow
• BioHack-2019, Saint-Petersburg, 2019, participant
• Data Analysis in R by Stepik
• Winter School Algorithms in Structural Bioinformatics (AlgoSB), January 2019, CIRM, Marseille
• Machine Learning, February-May 2019, CAE Institute for Smart Materials and Technologies TSU, Tomsk
• School of epidemiology and mixed methods research for young scientists, April 2019, Swiss TPH and SSMU, Tomsk
• linux introduction by Stepik
• Winter School "CompTech @ NSK WS 2018", 2018, NSU
• IV International Medical Tournament, Regional Stage, 2018, Tomsk, 2nd place
• II Medical Engineering School, 2018, Tomsk, 2nd place
• Hackathon "LifeCode" -2018, Novosibirsk, participant
• Regional Olympiad in Informatics, 2017, Tomsk, 3rd place
• Hackathon “Digital Hack”, 2017, Tomsk, 3rd place
• Debate in the framework of the 77th All-Russian Student Scientific Conference (dedicated to the memory of N.I. Pirogov), 2018, Tomsk, 1 place