Skip to content

Commit

Permalink
Update README.md
Browse files Browse the repository at this point in the history
  • Loading branch information
AlicenJoyHenning authored Sep 23, 2024
1 parent cdda522 commit 6ac72aa
Showing 1 changed file with 1 addition and 1 deletion.
2 changes: 1 addition & 1 deletion README.md
Original file line number Diff line number Diff line change
Expand Up @@ -21,7 +21,7 @@ For droplet-based protocols, ‘low quality’ cells are those that originate fr

<br>

```limiric``` is a quality control package that automates the sample-specific detection of damaged cells in one fast acting and highly reproducible function. It operates on the biological principle that damaged and healthy cells can be differentiated by the complexity of their mitochondrial and ribosomal gene expression, a complexity that can be effectively resolved through clustering in lower-dimensional space. Beyond predicting damaged cells, ```limiric``` offers functionality to estimate and correct for red blood cell contamination— an uncommon but significant artifact of single-cell isolation protocols for which no automated tool currently exists. If relevant to a user's investigation, ```limiric``` can also be used isolate immune (CD45^+) cell populations, a step performed prior to the detection and removal of damaged cells.
```limiric``` is a quality control package that automates the sample-specific detection of damaged cells in one fast acting and highly reproducible function. It operates on the biological principle that damaged and healthy cells can be differentiated by the complexity of their mitochondrial and ribosomal gene expression, a complexity that can be effectively resolved through clustering in lower-dimensional space. Beyond predicting damaged cells, ```limiric``` offers functionality to estimate and correct for red blood cell contamination— an uncommon but significant artifact of single-cell isolation protocols for which no automated tool currently exists. If relevant to a user's investigation, ```limiric``` can also be used isolate immune (CD45⁺) populations, a step performed prior to the detection and removal of damaged cells.

<br>

Expand Down

0 comments on commit 6ac72aa

Please sign in to comment.