DynamicMPNN

🔧 Code coming soon! We're finalizing the codebase and data processing pipeline for release.

The first deep learning inverse folding model explicitly trained to generate sequences that fold into multiple conformations

Citation

@article{abrudan2025dynamic_mpnn,
      title={Multi-state Protein Design with DynamicMPNN}, 
      author={Alex Abrudan and Sebastian Pujalte Ojeda and Chaitanya K. Joshi and Matthew Greenig and Felipe Engelberger and Alena Khmelinskaia and Jens Meiler and Michele Vendruscolo and Tuomas P. J. Knowles},
      year={2025},
      eprint={2507.21938},
      archivePrefix={arXiv},
      primaryClass={cs.LG},
      url={https://arxiv.org/abs/2507.21938}, 
}