diff --git a/.changeset/light-jars-cheat.md b/.changeset/light-jars-cheat.md
new file mode 100644
index 000000000000..c286810b4a22
--- /dev/null
+++ b/.changeset/light-jars-cheat.md
@@ -0,0 +1,5 @@
+---
+'astro': patch
+---
+
+Handle inlining non-string boolean environment variables
diff --git a/.changeset/spicy-pugs-wonder.md b/.changeset/spicy-pugs-wonder.md
new file mode 100644
index 000000000000..568538810eb8
--- /dev/null
+++ b/.changeset/spicy-pugs-wonder.md
@@ -0,0 +1,5 @@
+---
+'@astrojs/cloudflare': patch
+---
+
+Fix runtime env var handling
diff --git a/packages/astro/src/vite-plugin-env/index.ts b/packages/astro/src/vite-plugin-env/index.ts
index 8d5a9c1c3df8..75a37d693b85 100644
--- a/packages/astro/src/vite-plugin-env/index.ts
+++ b/packages/astro/src/vite-plugin-env/index.ts
@@ -31,7 +31,11 @@ function getPrivateEnv(
 		// Ignore public env var
 		if (envPrefixes.every((prefix) => !key.startsWith(prefix))) {
 			if (typeof process.env[key] !== 'undefined') {
-				const value = process.env[key];
+				let value = process.env[key];
+				// Replacements are always strings, so try to convert to strings here first
+				if (typeof value !== 'string') {
+					value = `${value}`;
+				}
 				// Boolean values should be inlined to support `export const prerender`
 				// We already know that these are NOT sensitive values, so inlining is safe
 				if (value === '0' || value === '1' || value === 'true' || value === 'false') {
diff --git a/packages/integrations/cloudflare/src/index.ts b/packages/integrations/cloudflare/src/index.ts
index fa064e0ac2f6..40ee006f3ed2 100644
--- a/packages/integrations/cloudflare/src/index.ts
+++ b/packages/integrations/cloudflare/src/index.ts
@@ -91,6 +91,14 @@ export default function createIntegration(args?: Options): AstroIntegration {
 					}
 					vite.ssr ||= {};
 					vite.ssr.target = 'webworker';
+
+					// Cloudflare env is only available per request. This isn't feasible for code that access env vars
+					// in a global way, so we shim their access as `process.env.*`. We will populate `process.env` later
+					// in its fetch handler.
+					vite.define = {
+						'process.env': 'process.env',
+						...vite.define,
+					};
 				}
 			},
 			'astro:build:ssr': ({ entryPoints }) => {
diff --git a/packages/integrations/cloudflare/test/basics.test.js b/packages/integrations/cloudflare/test/basics.test.js
index b97079b8f134..9aa78f98e4ca 100644
--- a/packages/integrations/cloudflare/test/basics.test.js
+++ b/packages/integrations/cloudflare/test/basics.test.js
@@ -2,7 +2,7 @@ import { loadFixture, runCLI } from './test-utils.js';
 import { expect } from 'chai';
 import * as cheerio from 'cheerio';
 
-describe.skip('Basic app', () => {
+describe('Basic app', () => {
 	/** @type {import('./test-utils').Fixture} */
 	let fixture;
 	/** @type {import('./test-utils').WranglerCLI} */