Design data and process for the AdaptyvBio protein design competition
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Updated
Dec 11, 2024 - Python
Design data and process for the AdaptyvBio protein design competition
MSAffect is a computational pipeline to evaluate the robustness of AlphaFold2 protein structure predictions under adversarial MSA perturbations to identify structural sensitivity and confidence shifts in neural-network-based folding.
A modular, extensible peptide design pipeline with target preparation, backbone generation, sequence design, scoring, and ranking. Full local CPU pipeline, and backend hooks for RFpeptides, ProteinMPNN/LigandMPNN, and ColabFold.
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