diff --git a/microprofile/cdi/src/main/java/io/helidon/microprofile/cdi/HelidonContainerInitializer.java b/microprofile/cdi/src/main/java/io/helidon/microprofile/cdi/HelidonContainerInitializer.java
index a17a3c2cbab..adc44a2918e 100644
--- a/microprofile/cdi/src/main/java/io/helidon/microprofile/cdi/HelidonContainerInitializer.java
+++ b/microprofile/cdi/src/main/java/io/helidon/microprofile/cdi/HelidonContainerInitializer.java
@@ -1,5 +1,5 @@
 /*
- * Copyright (c) 2019, 2020 Oracle and/or its affiliates.
+ * Copyright (c) 2019, 2022 Oracle and/or its affiliates.
  *
  * Licensed under the Apache License, Version 2.0 (the "License");
  * you may not use this file except in compliance with the License.
@@ -147,6 +147,9 @@ public SeContainerInitializer setClassLoader(ClassLoader classLoader) {
 
     @Override
     public SeContainer initialize() {
+        if (HelidonContainerImpl.isRuntime()) {
+            throw new IllegalStateException("Helidon CDI is already started, cannot create two instances in the same JVM");
+        }
         container.initInContext();
         return container.start();
     }
diff --git a/microprofile/server/src/main/java/io/helidon/microprofile/server/ServerCdiExtension.java b/microprofile/server/src/main/java/io/helidon/microprofile/server/ServerCdiExtension.java
index 68fbdc771df..23f4cfd0652 100644
--- a/microprofile/server/src/main/java/io/helidon/microprofile/server/ServerCdiExtension.java
+++ b/microprofile/server/src/main/java/io/helidon/microprofile/server/ServerCdiExtension.java
@@ -45,7 +45,6 @@
 import io.helidon.common.context.Contexts;
 import io.helidon.common.http.Http;
 import io.helidon.config.Config;
-import io.helidon.microprofile.cdi.BuildTimeStart;
 import io.helidon.microprofile.cdi.RuntimeStart;
 import io.helidon.webserver.KeyPerformanceIndicatorSupport;
 import io.helidon.webserver.Routing;
@@ -113,15 +112,6 @@ public class ServerCdiExtension implements Extension {
 
     private final Set<Routing.Builder> routingsWithKPIMetrics = new HashSet<>();
 
-    private void buildTime(@Observes @BuildTimeStart Object event) {
-        // update the status of server, as we may have been started without a builder being used
-        // such as when cdi.Main or SeContainerInitializer are used
-        if (!IN_PROGRESS_OR_RUNNING.compareAndSet(false, true)) {
-            throw new IllegalStateException("There is another builder in progress, or another Server running. "
-                                                    + "You cannot run more than one in parallel");
-        }
-    }
-
     private void prepareRuntime(@Observes @RuntimeStart Config config) {
         serverBuilder.config(config.get("server"));
         this.config = config;
@@ -171,6 +161,12 @@ private void registerKpiMetricsDeferrableRequestContextSetterHandler(JaxRsCdiExt
 
     private void startServer(@Observes @Priority(PLATFORM_AFTER + 100) @Initialized(ApplicationScoped.class) Object event,
                              BeanManager beanManager) {
+        // update the status of server, as we may have been started without a builder being used
+        // such as when cdi.Main or SeContainerInitializer are used
+        if (!IN_PROGRESS_OR_RUNNING.compareAndSet(false, true)) {
+            throw new IllegalStateException("There is another builder in progress, or another Server running. "
+                                                    + "You cannot run more than one in parallel");
+        }
 
         // make sure all configuration is in place
         if (null == jaxRsExecutorService) {
@@ -335,7 +331,7 @@ private void registerClasspathStaticContent(Config config) {
     private void stopServer(@Observes @Priority(PLATFORM_BEFORE) @BeforeDestroyed(ApplicationScoped.class) Object event) {
         try {
             if (started) {
-                doStop(event);
+                doStop();
             }
         } finally {
             // as there only can be a single CDI in a single JVM, once this CDI is shutting down, we
@@ -344,7 +340,7 @@ private void stopServer(@Observes @Priority(PLATFORM_BEFORE) @BeforeDestroyed(Ap
         }
     }
 
-    private void doStop(Object event) {
+    private void doStop() {
         if (null == webserver || !started) {
             // nothing to do
             return;