diff --git a/apis/python/setup.py b/apis/python/setup.py
index ce28d534ed..e1cb167f8e 100644
--- a/apis/python/setup.py
+++ b/apis/python/setup.py
@@ -326,8 +326,7 @@ def run(self):
     zip_safe=False,
     setup_requires=["pybind11"],
     install_requires=[
-        # Tracked in https://github.com/single-cell-data/TileDB-SOMA/issues/1785
-        "anndata != 0.10.0",
+        "anndata>=0.10.1",
         "attrs>=22.2",
         "numba>=0.58.0",
         "numpy<2.0",