Skip to content
@scbirlab

SCBIR Lab

README.md

Systems Chemical Biology of Infection and Resistance Laboratory

Logo of SCBIR lab

The SCBIR lab is based the Francis Crick Institute in London. We use large-scale genetics and chemical biology to study how pathogenic bacteria infect and evolve resistance to antibiotics.

Ultimately, we aim to enable antimicrobial therapies which exploit key weaknesses in the ability of pathogenic bacteria to infect and evolve resistance to antibiotics.

Our work focuses on these areas (click the links for more information):

Find out more about our research here!

Pinned Loading

  1. schemist schemist Public

    ⬢⬢⬢ Organizing and processing tables of chemical structures.

    Python 2

  2. yunta yunta Public

    🍐 Predicting protein-protein interactions and structures from multiple sequence alignments.

    Python 3

  3. crispio crispio Public

    🌱 Designing CRISPRi experiments in bacteria

    Python 1

  4. duvida duvida Public

    🧐 Calculating exact and approximate confidence and information metrics for deep learning on general purpose and chemistry tasks.

    Python

  5. vectome vectome Public

    🧬 Deterministic vector embedding of genomes.

    Python

  6. duvidnn duvidnn Public

    🧐 Deep learning with uncertainty for general purpose, chemistry, and taxonomic tasks.

    Python

Repositories

Showing 10 of 38 repositories
  • nf-crispriseq Public

    Calculate fitness from massive competition experiments using CRISPRi-seq.

    scbirlab/nf-crispriseq’s past year of commit activity
    Nextflow 0 MIT 0 1 1 Updated Jan 28, 2026
  • crispio Public

    🌱 Designing CRISPRi experiments in bacteria

    scbirlab/crispio’s past year of commit activity
    Python 0 MIT 1 0 0 Updated Jan 28, 2026
  • duvidnn Public

    🧐 Deep learning with uncertainty for general purpose, chemistry, and taxonomic tasks.

    scbirlab/duvidnn’s past year of commit activity
    Python 0 MIT 0 0 1 Updated Jan 20, 2026
  • vectome Public

    🧬 Deterministic vector embedding of genomes.

    scbirlab/vectome’s past year of commit activity
    Python 0 MIT 0 0 0 Updated Dec 22, 2025
  • nf-report Public

    Nextflow pipeline to screen druggable orthologs

    scbirlab/nf-report’s past year of commit activity
    Nextflow 0 MIT 0 0 1 Updated Dec 19, 2025
  • scbirlab.github.io Public

    Lab website

    scbirlab/scbirlab.github.io’s past year of commit activity
    Python 0 MIT 0 0 0 Updated Dec 19, 2025
  • nf-platereader-screen Public

    ➡️🏮 Process files from Biotek platereaders, normalise output, perform QC, make plots, and do statistical tests.

    scbirlab/nf-platereader-screen’s past year of commit activity
    Nextflow 0 MIT 0 0 0 Updated Nov 24, 2025
  • schemist Public

    ⬢⬢⬢ Organizing and processing tables of chemical structures.

    scbirlab/schemist’s past year of commit activity
    Python 2 MIT 0 0 0 Updated Nov 14, 2025
  • nf-sbrnaseq Public

    🧬 Process demultiplexed Illumina paired-end FASTQ files from multiple bacterial samples into a gene x cell count table.

    scbirlab/nf-sbrnaseq’s past year of commit activity
    Nextflow 0 MIT 0 0 0 Updated Oct 23, 2025
  • mic-predict Public

    Predict MICs against bacterial species with uncertainty

    scbirlab/mic-predict’s past year of commit activity
    Python 0 0 0 0 Updated Oct 22, 2025
View all repositories

People

This organization has no public members. You must be a member to see who’s a part of this organization.

Top languages

Loading…