diff --git a/chrome/browser/chromeos/chrome_browser_main_chromeos.cc b/chrome/browser/chromeos/chrome_browser_main_chromeos.cc
index 1a0253548f6f42..2c5ceb55572d6c 100644
--- a/chrome/browser/chromeos/chrome_browser_main_chromeos.cc
+++ b/chrome/browser/chromeos/chrome_browser_main_chromeos.cc
@@ -738,6 +738,9 @@ void ChromeBrowserMainPartsChromeos::PreMainMessageLoopRun() {
   chromeos::ResourceReporter::GetInstance()->StartMonitoring(
       task_manager::TaskManagerInterface::GetTaskManager());
 
+  if (!base::FeatureList::IsEnabled(features::kNativeNotifications))
+    notification_client_.reset(NotificationPlatformBridge::Create());
+
   ChromeBrowserMainPartsLinux::PreMainMessageLoopRun();
 }
 
@@ -886,9 +889,6 @@ void ChromeBrowserMainPartsChromeos::PreProfileInit() {
   message_center::MessageCenter::Get()->SetProductOSName(
       l10n_util::GetStringUTF16(IDS_SHORT_PRODUCT_OS_NAME));
 
-  if (!base::FeatureList::IsEnabled(features::kNativeNotifications))
-    notification_client_.reset(NotificationPlatformBridge::Create());
-
   // Register all installed components for regular update.
   base::PostTaskWithTraitsAndReplyWithResult(
       FROM_HERE, {base::MayBlock()},
@@ -1193,6 +1193,9 @@ void ChromeBrowserMainPartsChromeos::PostMainMessageLoopRun() {
   g_browser_process->platform_part()->browser_policy_connector_chromeos()->
       PreShutdown();
 
+  // Close the notification client before destroying the profile manager.
+  notification_client_.reset();
+
   // NOTE: Closes ash and destroys ash::Shell.
   ChromeBrowserMainPartsLinux::PostMainMessageLoopRun();
 
diff --git a/chrome/browser/notifications/arc_application_notifier_controller_chromeos.cc b/chrome/browser/notifications/arc_application_notifier_controller_chromeos.cc
index ef2a540ef5d9e1..8623f6b24013dc 100644
--- a/chrome/browser/notifications/arc_application_notifier_controller_chromeos.cc
+++ b/chrome/browser/notifications/arc_application_notifier_controller_chromeos.cc
@@ -7,9 +7,7 @@
 #include <set>
 
 #include "base/strings/utf_string_conversions.h"
-#include "chrome/browser/browser_process.h"
 #include "chrome/browser/profiles/profile.h"
-#include "chrome/browser/profiles/profile_manager.h"
 #include "ui/base/layout.h"
 #include "ui/display/display.h"
 #include "ui/display/screen.h"
@@ -33,6 +31,7 @@ ArcApplicationNotifierControllerChromeOS::
 
 std::vector<ash::mojom::NotifierUiDataPtr>
 ArcApplicationNotifierControllerChromeOS::GetNotifierList(Profile* profile) {
+  DCHECK(!profile->IsOffTheRecord());
   package_to_app_ids_.clear();
   icons_.clear();
   StopObserving();
@@ -112,14 +111,8 @@ void ArcApplicationNotifierControllerChromeOS::OnIconUpdated(ArcAppIcon* icon) {
 void ArcApplicationNotifierControllerChromeOS::StopObserving() {
   if (!last_profile_)
     return;
-
-  // This is also called from the destructor during shutdown. In that case, the
-  // profile manager and the profiles are already destroyed. (see Issue 783538)
-  if (g_browser_process->profile_manager() &&
-      g_browser_process->profile_manager()->IsValidProfile(last_profile_)) {
-    ArcAppListPrefs* const app_list = ArcAppListPrefs::Get(last_profile_);
-    app_list->RemoveObserver(this);
-  }
+  ArcAppListPrefs* const app_list = ArcAppListPrefs::Get(last_profile_);
+  app_list->RemoveObserver(this);
   last_profile_ = nullptr;
 }