diff --git a/news/9498.feature.rst b/news/9498.feature.rst
new file mode 100644
index 00000000000..bbaca4f98cc
--- /dev/null
+++ b/news/9498.feature.rst
@@ -0,0 +1 @@
+Cache http responses from trusted hosts.
diff --git a/src/pip/_internal/network/session.py b/src/pip/_internal/network/session.py
index 5021b8eefaa..93bb8912479 100644
--- a/src/pip/_internal/network/session.py
+++ b/src/pip/_internal/network/session.py
@@ -327,12 +327,20 @@ def add_trusted_host(self, host, source=None, suppress_logging=False):
         if host_port not in self.pip_trusted_origins:
             self.pip_trusted_origins.append(host_port)
 
+        self.mount(
+            build_url_from_netloc(host, scheme='http') + '/',
+            self._trusted_host_adapter
+        )
         self.mount(
             build_url_from_netloc(host) + '/',
             self._trusted_host_adapter
         )
         if not host_port[1]:
             # Mount wildcard ports for the same host.
+            self.mount(
+                build_url_from_netloc(host, scheme='http') + ':',
+                self._trusted_host_adapter
+            )
             self.mount(
                 build_url_from_netloc(host) + ':',
                 self._trusted_host_adapter