diff --git a/expression/integration_test/integration_test.go b/expression/integration_test/integration_test.go
index 11e9467a16001..a1839138b44e8 100644
--- a/expression/integration_test/integration_test.go
+++ b/expression/integration_test/integration_test.go
@@ -7846,3 +7846,16 @@ func TestIssue41733(t *testing.T) {
 	tk.MustQuery("show warnings").Check(testkit.Rows("Warning 1264 Out of range value for column 'c0' at row 1"))
 	tk.MustQuery("select * from t_big;").Check(testkit.Rows("18446744073709551615"))
 }
+
+func TestIssue45410(t *testing.T) {
+	store := testkit.CreateMockStore(t)
+	tk := testkit.NewTestKit(t, store)
+	tk.MustExec("create database testIssue45410")
+	defer tk.MustExec("drop database testIssue45410")
+	tk.MustExec("use testIssue45410")
+
+	tk.MustExec("DROP TABLE IF EXISTS t1;")
+	tk.MustExec("CREATE TABLE t1 (c1 TINYINT(1) UNSIGNED NOT NULL );")
+	tk.MustExec("INSERT INTO t1 VALUES (0);")
+	tk.MustQuery("SELECT c1>=CAST('-787360724' AS TIME) FROM t1;").Check(testkit.Rows("1"))
+}