diff --git a/errors.toml b/errors.toml
index 0dcbf9d6c550d..d170522ec4e6a 100644
--- a/errors.toml
+++ b/errors.toml
@@ -371,6 +371,11 @@ error = '''
 Deadlock found when trying to get lock; try restarting transaction
 '''
 
+["executor:1295"]
+error = '''
+This command is not supported in the prepared statement protocol yet
+'''
+
 ["executor:1317"]
 error = '''
 Query execution was interrupted
diff --git a/executor/errors.go b/executor/errors.go
index df9dbed68e2e4..31967c8a319e8 100644
--- a/executor/errors.go
+++ b/executor/errors.go
@@ -27,6 +27,7 @@ var (
 	ErrResultIsEmpty   = terror.ClassExecutor.New(mysql.ErrResultIsEmpty, mysql.MySQLErrName[mysql.ErrResultIsEmpty])
 	ErrBuildExecutor   = terror.ClassExecutor.New(mysql.ErrBuildExecutor, mysql.MySQLErrName[mysql.ErrBuildExecutor])
 	ErrBatchInsertFail = terror.ClassExecutor.New(mysql.ErrBatchInsertFail, mysql.MySQLErrName[mysql.ErrBatchInsertFail])
+	ErrUnsupportedPs   = terror.ClassExecutor.New(mysql.ErrUnsupportedPs, mysql.MySQLErrName[mysql.ErrUnsupportedPs])
 
 	ErrCantCreateUserWithGrant     = terror.ClassExecutor.New(mysql.ErrCantCreateUserWithGrant, mysql.MySQLErrName[mysql.ErrCantCreateUserWithGrant])
 	ErrPasswordNoMatch             = terror.ClassExecutor.New(mysql.ErrPasswordNoMatch, mysql.MySQLErrName[mysql.ErrPasswordNoMatch])
diff --git a/executor/executor_test.go b/executor/executor_test.go
index aa3427c739c36..eeafe0e9805ce 100644
--- a/executor/executor_test.go
+++ b/executor/executor_test.go
@@ -5620,6 +5620,11 @@ func (s *testClusterTableSuite) TearDownSuite(c *C) {
 	s.testSuiteWithCliBase.TearDownSuite(c)
 }
 
+func (s *testSuiteP1) TestPrepareLoadData(c *C) {
+	tk := testkit.NewTestKit(c, s.store)
+	tk.MustGetErrCode(`prepare stmt from "load data local infile '/tmp/load_data_test.csv' into table test";`, mysql.ErrUnsupportedPs)
+}
+
 func (s *testClusterTableSuite) TestSlowQuery(c *C) {
 	writeFile := func(file string, data string) {
 		f, err := os.OpenFile(file, os.O_CREATE|os.O_WRONLY, 0644)
diff --git a/executor/prepared.go b/executor/prepared.go
index aae6f4bd0a58d..4bde0554d7384 100644
--- a/executor/prepared.go
+++ b/executor/prepared.go
@@ -147,6 +147,10 @@ func (e *PrepareExec) Next(ctx context.Context, req *chunk.Chunk) error {
 		return ErrPrepareDDL
 	}
 
+	if _, ok := stmt.(*ast.LoadDataStmt); ok {
+		return ErrUnsupportedPs
+	}
+
 	// Prepare parameters should NOT over 2 bytes(MaxUint16)
 	// https://dev.mysql.com/doc/internals/en/com-stmt-prepare-response.html#packet-COM_STMT_PREPARE_OK.
 	if len(extractor.markers) > math.MaxUint16 {