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DESCRIPTION
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Package: SITH
Type: Package
Title: A Spatial Model of Intra-Tumor Heterogeneity
Version: 1.1.0
Date: 2021-01-03
Author: Phillip B. Nicol
Maintainer: Phillip B. Nicol <philnicol740@gmail.com>
Description: Implements a three-dimensional stochastic model of cancer growth and mutation similar to the one described in Waclaw et al. (2015) <doi:10.1038/nature14971>. Allows for interactive 3D visualizations of the simulated tumor. Provides a comprehensive summary of the spatial distribution of mutants within the tumor. Contains functions which create synthetic sequencing datasets from the generated tumor.
License: GPL (>= 2)
Depends: R (>= 3.6.0)
Imports:
Rcpp (>= 1.0.4),
scatterplot3d,
stats,
graphics,
grDevices
Suggests:
rgl,
igraph,
knitr,
rmarkdown,
testthat
LinkingTo: Rcpp
RoxygenNote: 7.1.1
VignetteBuilder: knitr
Encoding: UTF-8
URL: https://github.com/phillipnicol/SITH
BugReports: https://github.com/phillipnicol/SITH/issues