Can TSR inputs be used by Optiscaler?

[sanwablo]

There are a few games I like which only support Unreal Engine 5 Temporal Super Resolution (TSR). Can these inputs be used by Optiscaler? How? I tried installing it on Ender Magnolia and En Garde! but it doesn't seem to work out of the box in either game, though I see TSR inputs can be used for FSR4 in this list.

[davidbecam12]

Those usually are luma mod which intercepts taa or tsr input data and convert them to dlss/fsr. Optiscaler then hooks on that converted dlss/fsr again.
So no, optiscaler cannot just use default tsr inputs from ue5.