diff --git a/build_system/targets/packaging/build.py b/build_system/targets/packaging/build.py
index bf67ae54e..a43b930e1 100644
--- a/build_system/targets/packaging/build.py
+++ b/build_system/targets/packaging/build.py
@@ -19,7 +19,7 @@ def __init__(self, build_unit: BuildUnit, module: PythonPackageModule):
         :param build_unit:  The build unit from which the program should be run
         :param module:      The module, the program should be applied to
         """
-        super().__init__('build', '--no-isolation', '--wheel', module.root_directory)
+        super().__init__('build', '--wheel', module.root_directory)
         self.print_arguments(True)
-        self.add_dependencies('wheel', 'setuptools')
+        self.add_dependencies('wheel')
         self.set_build_unit(build_unit)
diff --git a/build_system/targets/packaging/requirements.txt b/build_system/targets/packaging/requirements.txt
index a2cb5b645..f54962e70 100644
--- a/build_system/targets/packaging/requirements.txt
+++ b/build_system/targets/packaging/requirements.txt
@@ -1,3 +1,2 @@
 build >= 1.2, < 1.3
-setuptools
 wheel >= 0.45, < 0.46