diff --git a/api/core/workflow/nodes/http_request/entities.py b/api/core/workflow/nodes/http_request/entities.py
index 36ded104c16a66..5e39ef79d139bf 100644
--- a/api/core/workflow/nodes/http_request/entities.py
+++ b/api/core/workflow/nodes/http_request/entities.py
@@ -1,4 +1,6 @@
+import mimetypes
 from collections.abc import Sequence
+from email.message import Message
 from typing import Any, Literal, Optional
 
 import httpx
@@ -7,14 +9,6 @@
 from configs import dify_config
 from core.workflow.nodes.base import BaseNodeData
 
-NON_FILE_CONTENT_TYPES = (
-    "application/json",
-    "application/xml",
-    "text/html",
-    "text/plain",
-    "application/x-www-form-urlencoded",
-)
-
 
 class HttpRequestNodeAuthorizationConfig(BaseModel):
     type: Literal["basic", "bearer", "custom"]
@@ -93,13 +87,53 @@ def __init__(self, response: httpx.Response):
 
     @property
     def is_file(self):
-        content_type = self.content_type
+        """
+        Determine if the response contains a file by checking:
+        1. Content-Disposition header (RFC 6266)
+        2. Content characteristics
+        3. MIME type analysis
+        """
+        content_type = self.content_type.split(";")[0].strip().lower()
         content_disposition = self.response.headers.get("content-disposition", "")
 
-        return "attachment" in content_disposition or (
-            not any(non_file in content_type for non_file in NON_FILE_CONTENT_TYPES)
-            and any(file_type in content_type for file_type in ("application/", "image/", "audio/", "video/"))
-        )
+        # Check if it's explicitly marked as an attachment
+        if content_disposition:
+            msg = Message()
+            msg["content-disposition"] = content_disposition
+            disp_type = msg.get_content_disposition()  # Returns 'attachment', 'inline', or None
+            filename = msg.get_filename()  # Returns filename if present, None otherwise
+            if disp_type == "attachment" or filename is not None:
+                return True
+
+        # For application types, try to detect if it's a text-based format
+        if content_type.startswith("application/"):
+            # Common text-based application types
+            if any(
+                text_type in content_type
+                for text_type in ("json", "xml", "javascript", "x-www-form-urlencoded", "yaml", "graphql")
+            ):
+                return False
+
+            # Try to detect if content is text-based by sampling first few bytes
+            try:
+                # Sample first 1024 bytes for text detection
+                content_sample = self.response.content[:1024]
+                content_sample.decode("utf-8")
+                # If we can decode as UTF-8 and find common text patterns, likely not a file
+                text_markers = (b"{", b"[", b"<", b"function", b"var ", b"const ", b"let ")
+                if any(marker in content_sample for marker in text_markers):
+                    return False
+            except UnicodeDecodeError:
+                # If we can't decode as UTF-8, likely a binary file
+                return True
+
+        # For other types, use MIME type analysis
+        main_type, _ = mimetypes.guess_type("dummy" + (mimetypes.guess_extension(content_type) or ""))
+        if main_type:
+            return main_type.split("/")[0] in ("application", "image", "audio", "video")
+
+        # For unknown types, check if it's a media type
+        return any(media_type in content_type for media_type in ("image/", "audio/", "video/"))
 
     @property
     def content_type(self) -> str:
diff --git a/api/tests/unit_tests/core/workflow/nodes/http_request/test_entities.py b/api/tests/unit_tests/core/workflow/nodes/http_request/test_entities.py
new file mode 100644
index 00000000000000..0f6b7e4ab6c1fd
--- /dev/null
+++ b/api/tests/unit_tests/core/workflow/nodes/http_request/test_entities.py
@@ -0,0 +1,140 @@
+from unittest.mock import Mock, PropertyMock, patch
+
+import httpx
+import pytest
+
+from core.workflow.nodes.http_request.entities import Response
+
+
+@pytest.fixture
+def mock_response():
+    response = Mock(spec=httpx.Response)
+    response.headers = {}
+    return response
+
+
+def test_is_file_with_attachment_disposition(mock_response):
+    """Test is_file when content-disposition header contains 'attachment'"""
+    mock_response.headers = {"content-disposition": "attachment; filename=test.pdf", "content-type": "application/pdf"}
+    response = Response(mock_response)
+    assert response.is_file
+
+
+def test_is_file_with_filename_disposition(mock_response):
+    """Test is_file when content-disposition header contains filename parameter"""
+    mock_response.headers = {"content-disposition": "inline; filename=test.pdf", "content-type": "application/pdf"}
+    response = Response(mock_response)
+    assert response.is_file
+
+
+@pytest.mark.parametrize("content_type", ["application/pdf", "image/jpeg", "audio/mp3", "video/mp4"])
+def test_is_file_with_file_content_types(mock_response, content_type):
+    """Test is_file with various file content types"""
+    mock_response.headers = {"content-type": content_type}
+    # Mock binary content
+    type(mock_response).content = PropertyMock(return_value=bytes([0x00, 0xFF] * 512))
+    response = Response(mock_response)
+    assert response.is_file, f"Content type {content_type} should be identified as a file"
+
+
+@pytest.mark.parametrize(
+    "content_type",
+    [
+        "application/json",
+        "application/xml",
+        "application/javascript",
+        "application/x-www-form-urlencoded",
+        "application/yaml",
+        "application/graphql",
+    ],
+)
+def test_text_based_application_types(mock_response, content_type):
+    """Test common text-based application types are not identified as files"""
+    mock_response.headers = {"content-type": content_type}
+    response = Response(mock_response)
+    assert not response.is_file, f"Content type {content_type} should not be identified as a file"
+
+
+@pytest.mark.parametrize(
+    ("content", "content_type"),
+    [
+        (b'{"key": "value"}', "application/octet-stream"),
+        (b"[1, 2, 3]", "application/unknown"),
+        (b"function test() {}", "application/x-unknown"),
+        (b"<root>test</root>", "application/binary"),
+        (b"var x = 1;", "application/data"),
+    ],
+)
+def test_content_based_detection(mock_response, content, content_type):
+    """Test content-based detection for text-like content"""
+    mock_response.headers = {"content-type": content_type}
+    type(mock_response).content = PropertyMock(return_value=content)
+    response = Response(mock_response)
+    assert not response.is_file, f"Content {content} with type {content_type} should not be identified as a file"
+
+
+@pytest.mark.parametrize(
+    ("content", "content_type"),
+    [
+        (bytes([0x00, 0xFF] * 512), "application/octet-stream"),
+        (bytes([0x89, 0x50, 0x4E, 0x47]), "application/unknown"),  # PNG magic numbers
+        (bytes([0xFF, 0xD8, 0xFF]), "application/binary"),  # JPEG magic numbers
+    ],
+)
+def test_binary_content_detection(mock_response, content, content_type):
+    """Test content-based detection for binary content"""
+    mock_response.headers = {"content-type": content_type}
+    type(mock_response).content = PropertyMock(return_value=content)
+    response = Response(mock_response)
+    assert response.is_file, f"Binary content with type {content_type} should be identified as a file"
+
+
+@pytest.mark.parametrize(
+    ("content_type", "expected_main_type"),
+    [
+        ("x-world/x-vrml", "model"),  # VRML 3D model
+        ("font/ttf", "application"),  # TrueType font
+        ("text/csv", "text"),  # CSV text file
+        ("unknown/xyz", None),  # Unknown type
+    ],
+)
+def test_mimetype_based_detection(mock_response, content_type, expected_main_type):
+    """Test detection using mimetypes.guess_type for non-application content types"""
+    mock_response.headers = {"content-type": content_type}
+    type(mock_response).content = PropertyMock(return_value=bytes([0x00]))  # Dummy content
+
+    with patch("core.workflow.nodes.http_request.entities.mimetypes.guess_type") as mock_guess_type:
+        # Mock the return value based on expected_main_type
+        if expected_main_type:
+            mock_guess_type.return_value = (f"{expected_main_type}/subtype", None)
+        else:
+            mock_guess_type.return_value = (None, None)
+
+        response = Response(mock_response)
+
+        # Check if the result matches our expectation
+        if expected_main_type in ("application", "image", "audio", "video"):
+            assert response.is_file, f"Content type {content_type} should be identified as a file"
+        else:
+            assert not response.is_file, f"Content type {content_type} should not be identified as a file"
+
+        # Verify that guess_type was called
+        mock_guess_type.assert_called_once()
+
+
+def test_is_file_with_inline_disposition(mock_response):
+    """Test is_file when content-disposition is 'inline'"""
+    mock_response.headers = {"content-disposition": "inline", "content-type": "application/pdf"}
+    # Mock binary content
+    type(mock_response).content = PropertyMock(return_value=bytes([0x00, 0xFF] * 512))
+    response = Response(mock_response)
+    assert response.is_file
+
+
+def test_is_file_with_no_content_disposition(mock_response):
+    """Test is_file when no content-disposition header is present"""
+    mock_response.headers = {"content-type": "application/pdf"}
+    # Mock binary content
+    type(mock_response).content = PropertyMock(return_value=bytes([0x00, 0xFF] * 512))
+    response = Response(mock_response)
+    assert response.is_file