diff --git a/entities.csv b/entities.csv
index 6330fe2e8..09109f6ae 100644
--- a/entities.csv
+++ b/entities.csv
@@ -71,6 +71,7 @@ BDKR
 BEST
 Beta_3_4_GTF
 BIRC
+BLVR
 BMP
 BMP_receptor
 BMP_receptor_type_I
@@ -117,12 +118,14 @@ Chemokine_receptor
 Chloride_calcium_activated_channels
 Chloride_channels
 Cholinesterase
+CHK
 CHRM
 CHRN
 CK2
 Clathrin
 CLCN
 CLIC
+CLK
 CNG
 CNKSR
 Cofilin
@@ -149,14 +152,17 @@ CTNNA
 CUL
 CXCL_ELR_negative
 CXCL_ELR_positive
+Creatine_kinase
 Cyclin
 Cyclin_A
 Cyclin_D
 Cyclin_E
 Cyclophilin
 Cytoplasmic_dynein
+DAPK
 DDR
 Death_receptor
+Deoxyribonucleoside_kinases
 Desmoglein
 DGC
 DGK
@@ -169,6 +175,7 @@ DYRK
 E2F
 E3_Ub_ligase
 EDN
+EFN
 EGFR_ligand
 EGR
 EIF2B
@@ -180,6 +187,8 @@ EIF4G
 ELA
 ENO
 Eotaxin
+EPHA
+EPHB
 Ephrin_receptor
 EPN
 ERBB
@@ -192,6 +201,7 @@ ETC_complex_III
 ETC_complex_I_supernumerary
 ETC_complex_IV
 ETC_complex_V
+ETNK
 ETS
 EXOC
 EXT
@@ -335,6 +345,7 @@ MAP2K
 MAP3K
 MAPK
 MCM
+MED
 MEF2
 MEK
 Metallothionein
@@ -342,6 +353,7 @@ MGAT
 Mitochondrial_Ribosome
 MKNK
 MMP
+MOB
 MRPL
 MRPS
 mTORC1
@@ -369,6 +381,7 @@ NCOA
 NCOR
 NDRG
 Neurexins
+Neuropeptides
 NFAT
 NFE
 NFkappaB
@@ -444,6 +457,7 @@ Phosphatase
 PI3K
 PI3K_p110
 PI3K_p85
+PI4K
 PIK3R_I
 PIM
 PKA
@@ -503,6 +517,7 @@ RFX
 RGL
 RHO
 RhoGDI
+RIPK
 RLR
 RNApo_I
 RNApo_II
@@ -511,6 +526,9 @@ ROCK
 ROR
 RPA
 RSK
+RSTK
+RSTK1
+RSTK2
 RTK
 RXR
 RYR
@@ -544,6 +562,7 @@ Sodium_channels
 Sodium_voltage_gated_channel_alpha_subunits
 Sodium_voltage_gated_channel_beta_subunits
 SOS
+SPHK
 SPRED
 SPRY
 SRC
@@ -553,8 +572,10 @@ STAT5
 STT3
 Sulfonylurea_receptor
 SWI_SNF
+TAC
 TAOK
 TAP
+TAT_associated_kinase
 TCF_LEF
 TCR
 TEAD
@@ -567,10 +588,12 @@ THR
 Thrombin_antithrombin
 TIAM
 TIF_IB
+TK
 TLR
 TN
 TNF
 TNFRSF
+TOP
 TOP2
 TPCN
 Troponin
diff --git a/equivalences.csv b/equivalences.csv
index 2eb52b58c..b0ccc2473 100644
--- a/equivalences.csv
+++ b/equivalences.csv
@@ -489,6 +489,8 @@ HGNC_GROUP,305,AQP
 HGNC_GROUP,306,VDAC
 HGNC_GROUP,307,CLIC
 HGNC_GROUP,314,GJ
+HGNC_GROUP,480,CLK
+HGNC_GROUP,546,EFN
 HGNC_GROUP,563,GABR
 HGNC_GROUP,581,Augmin
 HGNC_GROUP,622,Kinesin
@@ -497,11 +499,14 @@ HGNC_GROUP,641,ETC_complex_II
 HGNC_GROUP,642,ETC_complex_III
 HGNC_GROUP,643,ETC_complex_IV
 HGNC_GROUP,644,ETC_complex_V
+HGNC_GROUP,647,MOB
 HGNC_GROUP,854,Neuropeptide_receptor
 HGNC_GROUP,856,KCNT
 HGNC_GROUP,865,ANO
 HGNC_GROUP,866,BEST
 HGNC_GROUP,868,GLRA_GLRB
+HGNC_GROUP,1021,DAPK
+HGNC_GROUP,1050,TOP
 HGNC_GROUP,1149,ETC_complex_I_core
 HGNC_GROUP,1150,ETC_complex_I_supernumerary
 HGNC_GROUP,1158,LRRC8
@@ -514,6 +519,10 @@ HGNC_GROUP,1511,CACNG
 HGNC_GROUP,1512,CACNA1
 HGNC_GROUP,1514,CACNA2D
 HGNC_GROUP,1515,CACNB
+HGNC_GROUP,1699,Deoxyribonucleoside_kinases
+HGNC_GROUP,1901,TAC
+HGNC_GROUP,1902,Neuropeptides
+HGNC_GROUP,1908,EDN
 IP,IPR000074,Apolipoprotein
 IP,IPR000096,SAA
 IP,IPR000162,GRM
diff --git a/export/famplex.belns b/export/famplex.belns
index 3569f205d..0d1151bfe 100644
--- a/export/famplex.belns
+++ b/export/famplex.belns
@@ -2,8 +2,8 @@
 Keyword=FPLX
 NameString=FamPlex
 DomainString=Gene and Gene Products
-VersionString=20200121
-CreatedDateTime=2020-01-21T09:07:57
+VersionString=20200123
+CreatedDateTime=2020-01-23T22:36:43
 DescriptionString=FamPlex is a collection of resources for grounding biological entities from text and describing their hierarchical relationships.
 QueryValueURL=http://identifiers.org/fplx/
 
@@ -93,6 +93,7 @@ BCKDC|CGPR
 BDKR|CGPR
 BEST|CGPR
 BIRC|CGPR
+BLVR|CGPR
 BMP|CGPR
 BMP_receptor|CGPR
 BMP_receptor_type_I|CGPR
@@ -129,11 +130,13 @@ CDKN1|CGPR
 CDKN2|CGPR
 CEBP|CGPR
 CHEK|CGPR
+CHK|CGPR
 CHRM|CGPR
 CHRN|CGPR
 CK2|CGPR
 CLCN|CGPR
 CLIC|CGPR
+CLK|CGPR
 CNG|CGPR
 CNKSR|CGPR
 COL1|CGPR
@@ -172,12 +175,14 @@ Cholinesterase|CGPR
 Clathrin|CGPR
 Cofilin|CGPR
 Cohesin|CGPR
+Creatine_kinase|CGPR
 Cyclin|CGPR
 Cyclin_A|CGPR
 Cyclin_D|CGPR
 Cyclin_E|CGPR
 Cyclophilin|CGPR
 Cytoplasmic_dynein|CGPR
+DAPK|CGPR
 DDR|CGPR
 DGC|CGPR
 DGK|CGPR
@@ -188,10 +193,12 @@ DUSP|CGPR
 DVL|CGPR
 DYRK|CGPR
 Death_receptor|CGPR
+Deoxyribonucleoside_kinases|CGPR
 Desmoglein|CGPR
 E2F|CGPR
 E3_Ub_ligase|CGPR
 EDN|CGPR
+EFN|CGPR
 EGFR_ligand|CGPR
 EGR|CGPR
 EIF2B|CGPR
@@ -202,6 +209,8 @@ EIF4EBP|CGPR
 EIF4G|CGPR
 ELA|CGPR
 ENO|CGPR
+EPHA|CGPR
+EPHB|CGPR
 EPN|CGPR
 ERBB|CGPR
 ERK|CGPR
@@ -213,6 +222,7 @@ ETC_complex_IV|CGPR
 ETC_complex_I_core|CGPR
 ETC_complex_I_supernumerary|CGPR
 ETC_complex_V|CGPR
+ETNK|CGPR
 ETS|CGPR
 EXOC|CGPR
 EXT|CGPR
@@ -356,11 +366,13 @@ MAP2K|CGPR
 MAP3K|CGPR
 MAPK|CGPR
 MCM|CGPR
+MED|CGPR
 MEF2|CGPR
 MEK|CGPR
 MGAT|CGPR
 MKNK|CGPR
 MMP|CGPR
+MOB|CGPR
 MRPL|CGPR
 MRPS|CGPR
 MYH|CGPR
@@ -405,6 +417,7 @@ Na_K_ATPase|CGPR
 Natriuretic_peptide|CGPR
 Neurexins|CGPR
 Neuropeptide_receptor|CGPR
+Neuropeptides|CGPR
 Notch|CGPR
 OGT_family|CGPR
 OR|CGPR
@@ -457,6 +470,7 @@ PFN|CGPR
 PI3K|CGPR
 PI3K_p110|CGPR
 PI3K_p85|CGPR
+PI4K|CGPR
 PIK3R_I|CGPR
 PIM|CGPR
 PKA|CGPR
@@ -518,6 +532,7 @@ RFC|CGPR
 RFX|CGPR
 RGL|CGPR
 RHO|CGPR
+RIPK|CGPR
 RLR|CGPR
 RNApo_I|CGPR
 RNApo_II|CGPR
@@ -526,6 +541,9 @@ ROCK|CGPR
 ROR|CGPR
 RPA|CGPR
 RSK|CGPR
+RSTK|CGPR
+RSTK1|CGPR
+RSTK2|CGPR
 RTK|CGPR
 RXR|CGPR
 RYR|CGPR
@@ -558,6 +576,7 @@ SMURF|CGPR
 SNAI|CGPR
 SOD|CGPR
 SOS|CGPR
+SPHK|CGPR
 SPRED|CGPR
 SPRY|CGPR
 SRC|CGPR
@@ -570,8 +589,10 @@ Sodium_channels|CGPR
 Sodium_voltage_gated_channel_alpha_subunits|CGPR
 Sodium_voltage_gated_channel_beta_subunits|CGPR
 Sulfonylurea_receptor|CGPR
+TAC|CGPR
 TAOK|CGPR
 TAP|CGPR
+TAT_associated_kinase|CGPR
 TCF_LEF|CGPR
 TCR|CGPR
 TEAD|CGPR
@@ -583,10 +604,12 @@ THBS|CGPR
 THR|CGPR
 TIAM|CGPR
 TIF_IB|CGPR
+TK|CGPR
 TLR|CGPR
 TN|CGPR
 TNF|CGPR
 TNFRSF|CGPR
+TOP|CGPR
 TOP2|CGPR
 TPCN|CGPR
 TRP|CGPR
diff --git a/export/famplex.obo b/export/famplex.obo
index 8a6034d5f..62783147e 100644
--- a/export/famplex.obo
+++ b/export/famplex.obo
@@ -1,5 +1,5 @@
 format-version: 1.2
-date: 20:01:2020 17:58
+date: 23:01:2020 22:36
 
 [Term]
 id: FPLX:5_hydroxytryptamine_receptors_ionotropic
@@ -505,6 +505,7 @@ inverse_is_a: HGNC:ALG8
 id: FPLX:AMPK
 name: AMPK
 synonym: "AMPK" EXACT []
+synonym: "AMP-activated" EXACT []
 xref: BEL:"AMP Activated Protein Kinase Complex"
 xref: ECCODE:2.7.11.31
 xref: MEDSCAN:urn:agi-protfc:AMPK
@@ -1191,6 +1192,14 @@ inverse_is_a: HGNC:BIRC8
 inverse_is_a: HGNC:NAIP
 inverse_is_a: HGNC:XIAP
 
+[Term]
+id: FPLX:BLVR
+name: BLVR
+synonym: "BVR" EXACT []
+is_a: FPLX:root
+inverse_is_a: HGNC:BLVRA
+inverse_is_a: HGNC:BLVRB
+
 [Term]
 id: FPLX:BMP
 name: BMP
@@ -1422,6 +1431,7 @@ id: FPLX:CAMK
 name: CAMK
 synonym: "CaMK family" EXACT []
 synonym: "CaMK" EXACT []
+synonym: "CAMK" EXACT []
 xref: BEL:"CAMK Family"
 xref: ECCODE:2.7.11.17
 xref: NEXTPROT-FAMILY:03072
@@ -1437,9 +1447,19 @@ id: FPLX:CAMK2_complex
 name: CAMK2-complex
 synonym: "Ca(2+)-calmodulin-dependent protein kinase II" EXACT []
 synonym: "Ca(2+)/calmodulin-dependent kinase II" EXACT []
+synonym: "calmodulindependent kinase II" EXACT []
 synonym: "CaM kinase II" EXACT []
 synonym: "CaMK II" EXACT []
+synonym: "CAMK2" EXACT []
+synonym: "CaMK2" EXACT []
 synonym: "CaMKII" EXACT []
+synonym: "CAMKII" EXACT []
+synonym: "CaM serine/threonine kinase II" EXACT []
+synonym: "CAMK-II" EXACT []
+synonym: "CaMKII protein" EXACT []
+synonym: "CAM-KII" EXACT []
+synonym: "p-CaMKII" EXACT []
+synonym: "CaMK-II" EXACT []
 xref: BEL:"CAMK2 Complex"
 xref: IP:IPR013543
 xref: MEDSCAN:urn:agi-complex:CaM%20kinase%20II
@@ -1456,11 +1476,6 @@ has_part: HGNC:CAMK2G
 [Term]
 id: FPLX:CAMK2_family
 name: CAMK2-family
-synonym: "calmodulindependent kinase II" EXACT []
-synonym: "CAMK2" EXACT []
-synonym: "CaMK2" EXACT []
-synonym: "CAMKII" EXACT []
-synonym: "CaM serine/threonine kinase II" EXACT []
 xref: BEL:"CAMK2 Family"
 xref: IP:IPR013543
 xref: RE:R-HSA-417004
@@ -1801,10 +1816,10 @@ inverse_is_a: HGNC:CDK2
 id: FPLX:CDKN
 name: CDKN
 synonym: "CDKN" EXACT []
-synonym: "CKI" EXACT []
 synonym: "cyclin dependent kinase inhibitors" EXACT []
 synonym: "cyclin-dependent kinase inhibitor" EXACT []
 synonym: "cyclin-dependent protein kinase inhibitors" EXACT []
+synonym: "CKIs" EXACT []
 xref: NCIT:C18492
 xref: XFAM:PF02234
 is_a: FPLX:root
@@ -1816,6 +1831,7 @@ inverse_is_a: HGNC:CDKN3
 id: FPLX:CDKN1
 name: CDKN1
 synonym: "CDKN1" EXACT []
+synonym: "Cdkn1" EXACT []
 xref: IP:IPR003175
 xref: RE:R-HSA-8941923
 xref: RE:R-HSA-8942604
@@ -1932,6 +1948,16 @@ is_a: FPLX:root
 inverse_is_a: HGNC:ACHE
 inverse_is_a: HGNC:BCHE
 
+[Term]
+id: FPLX:CHK
+name: CHK
+synonym: "chk" EXACT []
+synonym: "ethanolamine kinase" EXACT []
+synonym: "choline kinase" EXACT []
+is_a: FPLX:root
+inverse_is_a: HGNC:CHKA
+inverse_is_a: HGNC:CHKB
+
 [Term]
 id: FPLX:CHRM
 name: CHRM
@@ -2033,6 +2059,16 @@ inverse_is_a: HGNC:CLIC4
 inverse_is_a: HGNC:CLIC5
 inverse_is_a: HGNC:CLIC6
 
+[Term]
+id: FPLX:CLK
+name: CLK
+xref: HGNC_GROUP:480
+is_a: FPLX:root
+inverse_is_a: HGNC:CLK1
+inverse_is_a: HGNC:CLK2
+inverse_is_a: HGNC:CLK3
+inverse_is_a: HGNC:CLK4
+
 [Term]
 id: FPLX:CNG
 name: CNG
@@ -2331,6 +2367,7 @@ synonym: "Casein kinase 1" EXACT []
 synonym: "casein kinase 1" EXACT []
 synonym: "casein kinase I" EXACT []
 synonym: "CSNK1" EXACT []
+synonym: "CK-I" EXACT []
 xref: BEL:"CSNK1 Family"
 xref: MEDSCAN:urn:agi-protfc:casein%20kinase%20I
 xref: NEXTPROT-FAMILY:03083
@@ -2425,6 +2462,18 @@ inverse_is_a: HGNC:CXCL6
 inverse_is_a: HGNC:CXCL8
 inverse_is_a: HGNC:PPBP
 
+[Term]
+id: FPLX:Creatine_kinase
+name: Creatine-kinase
+synonym: "creatine kinase" EXACT []
+is_a: FPLX:root
+inverse_is_a: HGNC:CKB
+inverse_is_a: HGNC:CKBE
+inverse_is_a: HGNC:CKM
+inverse_is_a: HGNC:CKMT1A
+inverse_is_a: HGNC:CKMT1B
+inverse_is_a: HGNC:CKMT2
+
 [Term]
 id: FPLX:Cyclin
 name: Cyclin
@@ -2551,6 +2600,19 @@ has_part: HGNC:DYNLL1
 has_part: HGNC:DYNLRB1
 has_part: HGNC:DYNLRB2
 
+[Term]
+id: FPLX:DAPK
+name: DAPK
+synonym: "DAPK" EXACT []
+synonym: "DAPk" EXACT []
+xref: HGNC_GROUP:1021
+is_a: FPLX:root
+inverse_is_a: HGNC:DAPK1
+inverse_is_a: HGNC:DAPK2
+inverse_is_a: HGNC:DAPK3
+inverse_is_a: HGNC:STK17A
+inverse_is_a: HGNC:STK17B
+
 [Term]
 id: FPLX:DDR
 name: DDR
@@ -2579,6 +2641,17 @@ inverse_is_a: HGNC:TNFRSF10C
 inverse_is_a: HGNC:TNFRSF10D
 inverse_is_a: HGNC:FAS
 
+[Term]
+id: FPLX:Deoxyribonucleoside_kinases
+name: Deoxyribonucleoside-kinases
+xref: HGNC_GROUP:1699
+is_a: FPLX:root
+inverse_is_a: HGNC:DCK
+inverse_is_a: HGNC:DGUOK
+inverse_is_a: FPLX:TK
+inverse_is_a: HGNC:TK1
+inverse_is_a: HGNC:TK2
+
 [Term]
 id: FPLX:Desmoglein
 name: Desmoglein
@@ -2630,6 +2703,7 @@ synonym: "DAG kinase" EXACT []
 synonym: "DGK" EXACT []
 synonym: "diacyl glycerol kinase" EXACT []
 synonym: "diacylglycerol kinase" EXACT []
+synonym: "Dgk" EXACT []
 xref: BEL:"DGK Family"
 xref: ECCODE:2.7.1.107
 xref: IP:IPR000756
@@ -2774,17 +2848,34 @@ name: EDN
 synonym: "endothelin" EXACT []
 synonym: "endothelins" EXACT []
 xref: BEL:"EDN Family"
+xref: HGNC_GROUP:1908
 xref: IP:IPR001928
 xref: IP:IPR019764
 xref: IP:IPR020475
 xref: MEDSCAN:urn:agi-protfc:endothelin
 xref: XFAM:PF00322
 xref: RE:R-HSA-388544
-is_a: FPLX:root
+is_a: FPLX:Neuropeptides
 inverse_is_a: HGNC:EDN1
 inverse_is_a: HGNC:EDN2
 inverse_is_a: HGNC:EDN3
 
+[Term]
+id: FPLX:EFN
+name: EFN
+synonym: "ephrin" EXACT []
+synonym: "ephrins" EXACT []
+xref: HGNC_GROUP:546
+is_a: FPLX:root
+inverse_is_a: HGNC:EFNA1
+inverse_is_a: HGNC:EFNA2
+inverse_is_a: HGNC:EFNA3
+inverse_is_a: HGNC:EFNA4
+inverse_is_a: HGNC:EFNA5
+inverse_is_a: HGNC:EFNB1
+inverse_is_a: HGNC:EFNB2
+inverse_is_a: HGNC:EFNB3
+
 [Term]
 id: FPLX:EGFR_ligand
 name: EGFR-ligand
@@ -2924,19 +3015,9 @@ inverse_is_a: HGNC:CCL24
 inverse_is_a: HGNC:CCL26
 
 [Term]
-id: FPLX:Ephrin_receptor
-name: Ephrin-receptor
-synonym: "Eph receptor" EXACT []
-synonym: "Eph receptors" EXACT []
-synonym: "ephrin receptor" EXACT []
-xref: BEL:"Ephrin Receptor Family"
-xref: IP:IPR001090
-xref: IP:IPR001426
-xref: IP:IPR016257
-xref: IP:IPR027936
-xref: NCIT:C18606
-xref: NEXTPROT-FAMILY:03124
-is_a: FPLX:root
+id: FPLX:EPHA
+name: EPHA
+is_a: FPLX:Ephrin_receptor
 inverse_is_a: HGNC:EPHA1
 inverse_is_a: HGNC:EPHA2
 inverse_is_a: HGNC:EPHA3
@@ -2945,12 +3026,35 @@ inverse_is_a: HGNC:EPHA5
 inverse_is_a: HGNC:EPHA6
 inverse_is_a: HGNC:EPHA7
 inverse_is_a: HGNC:EPHA8
+inverse_is_a: HGNC:EPHA10
+
+[Term]
+id: FPLX:EPHB
+name: EPHB
+synonym: "EphB receptor" EXACT []
+is_a: FPLX:Ephrin_receptor
 inverse_is_a: HGNC:EPHB1
 inverse_is_a: HGNC:EPHB2
 inverse_is_a: HGNC:EPHB3
 inverse_is_a: HGNC:EPHB4
 inverse_is_a: HGNC:EPHB6
-inverse_is_a: HGNC:EPHA10
+
+[Term]
+id: FPLX:Ephrin_receptor
+name: Ephrin-receptor
+synonym: "Eph receptor" EXACT []
+synonym: "Eph receptors" EXACT []
+synonym: "ephrin receptor" EXACT []
+xref: BEL:"Ephrin Receptor Family"
+xref: IP:IPR001090
+xref: IP:IPR001426
+xref: IP:IPR016257
+xref: IP:IPR027936
+xref: NCIT:C18606
+xref: NEXTPROT-FAMILY:03124
+is_a: FPLX:root
+inverse_is_a: FPLX:EPHA
+inverse_is_a: FPLX:EPHB
 
 [Term]
 id: FPLX:EPN
@@ -2994,7 +3098,6 @@ synonym: "Erk1/2" EXACT []
 synonym: "ERKs" EXACT []
 synonym: "Extracellular Signal Regulated Kinase" EXACT []
 synonym: "extracellular signal-regulated kinase" EXACT []
-synonym: "MAPK" EXACT []
 synonym: "phospho-ERK1/2" EXACT []
 synonym: "p44 and p42" EXACT []
 synonym: "p42 and p44" EXACT []
@@ -3004,6 +3107,7 @@ synonym: "p42(mapk) and p44(mapk)" EXACT []
 synonym: "p42 and p38 MAPK" EXACT []
 synonym: "p42 and p38 MAP kinases" EXACT []
 synonym: "p42 and p38 MAPKs" EXACT []
+synonym: "p42/44" EXACT []
 xref: BEL:"MAPK Erk1/2 Family"
 xref: BEL:"MAPK Erk1/3 Family"
 xref: IP:IPR008349
@@ -3031,6 +3135,7 @@ id: FPLX:ESR
 name: ESR
 synonym: "ER" EXACT []
 synonym: "ESR" EXACT []
+synonym: "hER" EXACT []
 xref: BEL:"ESR Family"
 is_a: FPLX:root
 inverse_is_a: HGNC:ESR1
@@ -3188,6 +3293,13 @@ xref: HGNC_GROUP:644
 xref: MESH:D025261
 is_a: FPLX:root
 
+[Term]
+id: FPLX:ETNK
+name: ETNK
+is_a: FPLX:root
+inverse_is_a: HGNC:ETNK1
+inverse_is_a: HGNC:ETNK2
+
 [Term]
 id: FPLX:ETS
 name: ETS
@@ -4805,7 +4917,10 @@ is_a: FPLX:root
 [Term]
 id: FPLX:IKK_complex
 name: IKK-complex
+synonym: "IkappaB kinase" EXACT []
 synonym: "IKK complex" EXACT []
+synonym: "IKK" EXACT []
+synonym: "IκB kinase" EXACT []
 xref: BEL:"IkappaB Kinase Complex"
 xref: MEDSCAN:urn:agi-complex:IKK%20complex
 xref: RE:R-HSA-1168621
@@ -4823,9 +4938,6 @@ has_part: HGNC:IKBKG
 [Term]
 id: FPLX:IKK_family
 name: IKK-family
-synonym: "IkappaB kinase" EXACT []
-synonym: "IKK" EXACT []
-synonym: "IκB kinase" EXACT []
 xref: BEL:"IkappaB Kinase Family"
 xref: NCIT:C104199
 xref: NEXTPROT-FAMILY:03104
@@ -5067,6 +5179,7 @@ synonym: "JNK MAPK" EXACT []
 synonym: "JNK" EXACT []
 synonym: "JNK1/2" EXACT []
 synonym: "JNKs" EXACT []
+synonym: "SAPK" EXACT []
 xref: BEL:"MAPK JNK Family"
 xref: IP:IPR008351
 xref: MEDSCAN:urn:agi-aopfc:0000473
@@ -5523,6 +5636,7 @@ id: FPLX:MAPK
 name: MAPK
 synonym: "MAP kinase" EXACT []
 synonym: "MAP kinases" EXACT []
+synonym: "MAPK" EXACT []
 synonym: "MAPKs" EXACT []
 synonym: "mitogen activated protein kinase" EXACT []
 synonym: "mitogen activated protein kinases" EXACT []
@@ -5560,6 +5674,44 @@ inverse_is_a: HGNC:MCM8
 inverse_is_a: HGNC:MCM9
 inverse_is_a: HGNC:MCMDC2
 
+[Term]
+id: FPLX:MED
+name: MED
+is_a: FPLX:root
+has_part: HGNC:CCNC
+has_part: HGNC:CDK8
+has_part: HGNC:CDK19
+has_part: HGNC:MED1
+has_part: HGNC:MED29
+has_part: HGNC:MED27
+has_part: HGNC:MED4
+has_part: HGNC:MED24
+has_part: HGNC:MED6
+has_part: HGNC:MED7
+has_part: HGNC:MED8
+has_part: HGNC:MED9
+has_part: HGNC:MED10
+has_part: HGNC:MED11
+has_part: HGNC:MED12
+has_part: HGNC:MED12L
+has_part: HGNC:MED13
+has_part: HGNC:MED13L
+has_part: HGNC:MED14
+has_part: HGNC:MED15
+has_part: HGNC:MED16
+has_part: HGNC:MED17
+has_part: HGNC:MED18
+has_part: HGNC:MED19
+has_part: HGNC:MED20
+has_part: HGNC:MED21
+has_part: HGNC:MED22
+has_part: HGNC:MED23
+has_part: HGNC:MED25
+has_part: HGNC:MED26
+has_part: HGNC:MED28
+has_part: HGNC:MED30
+has_part: HGNC:MED31
+
 [Term]
 id: FPLX:MEF2
 name: MEF2
@@ -5702,6 +5854,19 @@ inverse_is_a: HGNC:MMP26
 inverse_is_a: HGNC:MMP27
 inverse_is_a: HGNC:MMP28
 
+[Term]
+id: FPLX:MOB
+name: MOB
+xref: HGNC_GROUP:647
+is_a: FPLX:root
+inverse_is_a: HGNC:MOB1A
+inverse_is_a: HGNC:MOB1B
+inverse_is_a: HGNC:MOB2
+inverse_is_a: HGNC:MOB3A
+inverse_is_a: HGNC:MOB3B
+inverse_is_a: HGNC:MOB3C
+inverse_is_a: HGNC:MOB4
+
 [Term]
 id: FPLX:MRPL
 name: MRPL
@@ -5837,6 +6002,7 @@ synonym: "Myosin heavy chain" EXACT []
 synonym: "myosin heavy chain" EXACT []
 synonym: "Myosin heavy chains" EXACT []
 synonym: "myosin heavy chains" EXACT []
+synonym: "Mhc" EXACT []
 xref: BEL:"MYH Family"
 xref: MEDSCAN:urn:agi-protfc:myosin%20heavy%20chain
 is_a: FPLX:Myosin_family
@@ -6068,7 +6234,7 @@ synonym: "natriuretic peptide" EXACT []
 synonym: "Natriuretic Peptides" EXACT []
 synonym: "Natriuretic peptides" EXACT []
 synonym: "natriuretic peptides" EXACT []
-is_a: FPLX:root
+is_a: FPLX:Neuropeptides
 inverse_is_a: HGNC:NPPA
 inverse_is_a: HGNC:NPPB
 inverse_is_a: HGNC:NPPC
@@ -6126,6 +6292,76 @@ inverse_is_a: HGNC:NRXN1
 inverse_is_a: HGNC:NRXN2
 inverse_is_a: HGNC:NRXN3
 
+[Term]
+id: FPLX:Neuropeptides
+name: Neuropeptides
+xref: HGNC_GROUP:1902
+is_a: FPLX:root
+inverse_is_a: HGNC:ADCYAP1
+inverse_is_a: HGNC:ADM
+inverse_is_a: HGNC:ADM2
+inverse_is_a: HGNC:AGRP
+inverse_is_a: HGNC:AGT
+inverse_is_a: HGNC:APLN
+inverse_is_a: HGNC:AVP
+inverse_is_a: HGNC:CALCA
+inverse_is_a: HGNC:CALCB
+inverse_is_a: HGNC:CCK
+inverse_is_a: HGNC:CHGA
+inverse_is_a: HGNC:CRH
+inverse_is_a: FPLX:EDN
+inverse_is_a: HGNC:GAL
+inverse_is_a: HGNC:GALP
+inverse_is_a: HGNC:GAST
+inverse_is_a: HGNC:GHRH
+inverse_is_a: HGNC:GHRL
+inverse_is_a: HGNC:GIP
+inverse_is_a: HGNC:GNRH1
+inverse_is_a: HGNC:GNRH2
+inverse_is_a: HGNC:GRP
+inverse_is_a: HGNC:HCRT
+inverse_is_a: HGNC:IAPP
+inverse_is_a: HGNC:IGF1
+inverse_is_a: HGNC:IGF2
+inverse_is_a: HGNC:INS
+inverse_is_a: HGNC:KISS1
+inverse_is_a: HGNC:KNG1
+inverse_is_a: HGNC:LEP
+inverse_is_a: HGNC:MLN
+inverse_is_a: HGNC:NMS
+inverse_is_a: HGNC:NMU
+inverse_is_a: HGNC:NPB
+inverse_is_a: HGNC:NPFF
+inverse_is_a: HGNC:NPS
+inverse_is_a: HGNC:NPVF
+inverse_is_a: HGNC:NPW
+inverse_is_a: HGNC:NPY
+inverse_is_a: HGNC:NTS
+inverse_is_a: HGNC:OXT
+inverse_is_a: HGNC:PDYN
+inverse_is_a: HGNC:PENK
+inverse_is_a: HGNC:PMCH
+inverse_is_a: HGNC:PNOC
+inverse_is_a: HGNC:POMC
+inverse_is_a: HGNC:PPY
+inverse_is_a: HGNC:PRL
+inverse_is_a: HGNC:PRLH
+inverse_is_a: HGNC:PTHLH
+inverse_is_a: HGNC:PYY
+inverse_is_a: HGNC:RLN1
+inverse_is_a: HGNC:RLN2
+inverse_is_a: HGNC:RLN3
+inverse_is_a: HGNC:SCT
+inverse_is_a: HGNC:SST
+inverse_is_a: FPLX:TAC
+inverse_is_a: FPLX:Natriuretic_peptide
+inverse_is_a: HGNC:TRH
+inverse_is_a: HGNC:UCN
+inverse_is_a: HGNC:UCN2
+inverse_is_a: HGNC:UCN3
+inverse_is_a: HGNC:UTS2
+inverse_is_a: HGNC:VIP
+
 [Term]
 id: FPLX:NFAT
 name: NFAT
@@ -7043,6 +7279,8 @@ synonym: "p38 MAPKs" EXACT []
 synonym: "p38" EXACT []
 synonym: "p38-MAPK" EXACT []
 synonym: "p38MAPK" EXACT []
+synonym: "p-38" EXACT []
+synonym: "p38 SAPK" EXACT []
 xref: BEL:"MAPK p38 Family"
 xref: IP:IPR008352
 xref: MEDSCAN:urn:agi-aopfc:0000477
@@ -7084,6 +7322,7 @@ synonym: "P70RSK" EXACT []
 synonym: "p70RSK" EXACT []
 synonym: "P70S6K" EXACT []
 synonym: "S6K" EXACT []
+synonym: "s6k" EXACT []
 xref: BEL:"RPS6KB Family"
 xref: MEDSCAN:urn:agi-protfc:p70rsk
 is_a: FPLX:RSK
@@ -7404,6 +7643,8 @@ has_part: HGNC:PDGFD
 id: FPLX:PDGFR
 name: PDGFR
 synonym: "PDGFR" EXACT []
+synonym: "derived growth factor" EXACT []
+synonym: "PDGF receptors" EXACT []
 xref: BEL:"PDGFR Family"
 xref: NCIT:C17322
 xref: RE:R-HSA-186769
@@ -7559,6 +7800,9 @@ synonym: "PI 3-kinases" EXACT []
 synonym: "PI3-kinase" EXACT []
 synonym: "PI3K" EXACT []
 synonym: "PI3Kinase" EXACT []
+synonym: "phosphoinositide 3-kinase" EXACT []
+synonym: "phosphoinositide-3 kinase" EXACT []
+synonym: "Phosphoinositide 3-kinase" EXACT []
 xref: BEL:"p85/p110 PI3Kinase Complex"
 xref: MEDSCAN:urn:agi-aopfc:0000447
 xref: MEDSCAN:urn:agi-complex:prophash-285b9ff3749679e4d6266406a20973aa
@@ -7590,6 +7834,15 @@ is_a: FPLX:PIK3R_I
 inverse_is_a: HGNC:PIK3R1
 inverse_is_a: HGNC:PIK3R2
 
+[Term]
+id: FPLX:PI4K
+name: PI4K
+synonym: "phosphatidylinositol 4-kinase" EXACT []
+synonym: "PI4K" EXACT []
+is_a: FPLX:root
+inverse_is_a: HGNC:PI4KA
+inverse_is_a: HGNC:PI4KB
+
 [Term]
 id: FPLX:PIK3R_I
 name: PIK3R-I
@@ -8137,6 +8390,8 @@ synonym: "Protein kinase A catalytic subunit" EXACT []
 synonym: "protein kinase A catalytic subunit" EXACT []
 synonym: "Protein kinase A catalytic subunits" EXACT []
 synonym: "protein kinase A catalytic subunits" EXACT []
+synonym: "cAK" EXACT []
+synonym: "PKA C-alpha" EXACT []
 xref: BEL:"PRKA Family"
 xref: SIGNOR:SIGNOR-PF17
 part_of: FPLX:PKA
@@ -8390,6 +8645,8 @@ inverse_is_a: HGNC:IFT22
 id: FPLX:RAC
 name: RAC
 synonym: "RAC" EXACT []
+synonym: "rac" EXACT []
+synonym: "Rac" EXACT []
 xref: BEL:"RAC Family"
 xref: NEXTPROT-FAMILY:03066
 is_a: FPLX:root
@@ -8403,6 +8660,7 @@ id: FPLX:RAF
 name: RAF
 synonym: "RAF" EXACT []
 synonym: "Raf" EXACT []
+synonym: "raf protein" EXACT []
 xref: BEL:"RAF Family"
 xref: NEXTPROT-FAMILY:03114
 xref: RE:R-HSA-5672708
@@ -8635,6 +8893,14 @@ inverse_is_a: HGNC:ARHGDIA
 inverse_is_a: HGNC:ARHGDIB
 inverse_is_a: HGNC:ARHGDIG
 
+[Term]
+id: FPLX:RIPK
+name: RIPK
+synonym: "RIPK" EXACT []
+is_a: FPLX:root
+inverse_is_a: HGNC:RIPK1
+inverse_is_a: HGNC:RIPK2
+
 [Term]
 id: FPLX:RLR
 name: RLR
@@ -8743,6 +9009,35 @@ is_a: FPLX:root
 inverse_is_a: FPLX:P90RSK
 inverse_is_a: FPLX:P70S6K
 
+[Term]
+id: FPLX:RSTK
+name: RSTK
+is_a: FPLX:root
+inverse_is_a: FPLX:RSTK1
+inverse_is_a: FPLX:RSTK2
+
+[Term]
+id: FPLX:RSTK1
+name: RSTK1
+is_a: FPLX:RSTK
+inverse_is_a: HGNC:ACVRL1
+inverse_is_a: HGNC:ACVR1
+inverse_is_a: HGNC:ACVR1B
+inverse_is_a: HGNC:ACVR1C
+inverse_is_a: HGNC:BMPR1A
+inverse_is_a: HGNC:BMPR1B
+inverse_is_a: HGNC:TGFBR1
+
+[Term]
+id: FPLX:RSTK2
+name: RSTK2
+is_a: FPLX:RSTK
+inverse_is_a: HGNC:ACVR2A
+inverse_is_a: HGNC:ACVR2B
+inverse_is_a: HGNC:AMHR2
+inverse_is_a: HGNC:BMPR2
+inverse_is_a: HGNC:TGFBR2
+
 [Term]
 id: FPLX:RTK
 name: RTK
@@ -9185,6 +9480,16 @@ is_a: FPLX:root
 inverse_is_a: HGNC:SOS1
 inverse_is_a: HGNC:SOS2
 
+[Term]
+id: FPLX:SPHK
+name: SPHK
+synonym: "Sphingosine kinase" EXACT []
+synonym: "sphingosine kinase" EXACT []
+synonym: "SphK" EXACT []
+is_a: FPLX:root
+inverse_is_a: HGNC:SPHK1
+inverse_is_a: HGNC:SPHK2
+
 [Term]
 id: FPLX:SPRED
 name: SPRED
@@ -9210,6 +9515,7 @@ inverse_is_a: HGNC:SPRY4
 id: FPLX:SRC
 name: SRC
 synonym: "SFK" EXACT []
+synonym: "SFKs" EXACT []
 synonym: "Src family kinase" EXACT []
 synonym: "Src family" EXACT []
 synonym: "src kinases" EXACT []
@@ -9336,6 +9642,15 @@ has_part: HGNC:ACTL6A
 has_part: HGNC:ACTL6B
 has_part: HGNC:HLTF
 
+[Term]
+id: FPLX:TAC
+name: TAC
+xref: HGNC_GROUP:1901
+is_a: FPLX:Neuropeptides
+inverse_is_a: HGNC:TAC1
+inverse_is_a: HGNC:TAC3
+inverse_is_a: HGNC:TAC4
+
 [Term]
 id: FPLX:TAOK
 name: TAOK
@@ -9357,6 +9672,13 @@ inverse_is_a: HGNC:TAP1
 inverse_is_a: HGNC:TAP2
 inverse_is_a: HGNC:ABCB9
 
+[Term]
+id: FPLX:TAT_associated_kinase
+name: TAT-associated-kinase
+is_a: FPLX:root
+has_part: HGNC:CDK9
+has_part: HGNC:CCNT1
+
 [Term]
 id: FPLX:TCF_LEF
 name: TCF-LEF
@@ -9544,6 +9866,12 @@ has_part: HGNC:TAF1B
 has_part: HGNC:TAF1C
 has_part: HGNC:TBP
 
+[Term]
+id: FPLX:TK
+name: TK
+synonym: "dTK" EXACT []
+is_a: FPLX:Deoxyribonucleoside_kinases
+
 [Term]
 id: FPLX:TLR
 name: TLR
@@ -9620,6 +9948,18 @@ inverse_is_a: HGNC:TNFRSF19
 inverse_is_a: HGNC:TNFRSF21
 inverse_is_a: HGNC:TNFRSF25
 
+[Term]
+id: FPLX:TOP
+name: TOP
+synonym: "topoisomerase" EXACT []
+xref: HGNC_GROUP:1050
+is_a: FPLX:root
+inverse_is_a: HGNC:TOP1
+inverse_is_a: HGNC:TOP1MT
+inverse_is_a: FPLX:TOP2
+inverse_is_a: HGNC:TOP3A
+inverse_is_a: HGNC:TOP3B
+
 [Term]
 id: FPLX:TOP2
 name: TOP2
@@ -9639,7 +9979,7 @@ xref: IP:IPR024946
 xref: IP:IPR031660
 xref: IP:IPR034157
 xref: NCIT:C18434
-is_a: FPLX:root
+is_a: FPLX:TOP
 inverse_is_a: HGNC:TOP2A
 inverse_is_a: HGNC:TOP2B
 
diff --git a/export/hgnc_symbol_map.csv b/export/hgnc_symbol_map.csv
index 1ffc2a969..af1ce2168 100644
--- a/export/hgnc_symbol_map.csv
+++ b/export/hgnc_symbol_map.csv
@@ -44,8 +44,11 @@ ACTN2,164
 ACTN3,165
 ACTN4,166
 ACVR1,171
+ACVR1B,172
+ACVR1C,18123
 ACVR2A,173
 ACVR2B,174
+ACVRL1,175
 ADCY1,232
 ADCY10,21285
 ADCY2,233
@@ -56,6 +59,7 @@ ADCY6,237
 ADCY7,238
 ADCY8,239
 ADCY9,240
+ADCYAP1,241
 ADH1A,249
 ADH1B,250
 ADH1C,251
@@ -65,6 +69,7 @@ ADH6,255
 ADH7,256
 ADHFE1,16354
 ADM,259
+ADM2,28898
 ADORA1,262
 ADORA2A,263
 ADORA2B,264
@@ -78,6 +83,8 @@ ADRA2C,283
 ADRB1,285
 ADRB2,286
 ADRB3,288
+AGRP,330
+AGT,333
 AKT1,391
 AKT2,392
 AKT3,393
@@ -110,6 +117,7 @@ ALG5,20266
 ALG6,23157
 ALG8,23161
 ALG9,15672
+AMHR2,465
 ANAPC1,19988
 ANAPC10,24077
 ANAPC11,14452
@@ -141,6 +149,7 @@ AP3D1,568
 AP3S1,2013
 AP3S2,571
 APH1A,29509
+APLN,16665
 APOA1,600
 APOA2,601
 APOA4,602
@@ -248,6 +257,7 @@ ATP5PD,845
 ATP5PF,847
 ATP5PO,850
 ATP7A,869
+AVP,894
 AXIN1,903
 AXIN2,904
 AXL,905
@@ -300,6 +310,8 @@ BIRC5,593
 BIRC6,13516
 BIRC7,13702
 BIRC8,14878
+BLVRA,1062
+BLVRB,1063
 BMI1,1066
 BMP1,1067
 BMP10,20869
@@ -363,6 +375,8 @@ CACNG5,1409
 CACNG6,13625
 CACNG7,13626
 CACNG8,13628
+CALCA,1437
+CALCB,1438
 CALM1,1442
 CALM2,1445
 CALM3,1449
@@ -413,6 +427,7 @@ CAV3,1529
 CBX2,1552
 CBX4,1554
 CBX8,15962
+CCK,1569
 CCL1,10609
 CCL11,10610
 CCL13,10611
@@ -583,6 +598,9 @@ CGB3,1886
 CHAD,1909
 CHEK1,1925
 CHEK2,16627
+CHGA,1929
+CHKA,1937
+CHKB,1938
 CHPF,24291
 CHPF2,29270
 CHRM1,1950
@@ -609,6 +627,12 @@ CHRNG,1967
 CHSY1,17198
 CHSY3,24293
 CHUK,1974
+CKB,1991
+CKBE,1992
+CKM,1994
+CKMT1A,31736
+CKMT1B,1995
+CKMT2,1996
 CLCN1,2019
 CLCN2,2020
 CLCN3,2021
@@ -625,6 +649,11 @@ CLIC4,13518
 CLIC5,13517
 CLIC6,2065
 CLINT1,23186
+CLK1,2068
+CLK2,2069
+CLK3,2071
+CLK4,13659
+CLOCK,2082
 CLTA,2090
 CLTB,2091
 CLTC,2092
@@ -679,12 +708,14 @@ CREB3L3,18855
 CREB3L4,18854
 CREB5,16844
 CREM,2352
+CRH,2355
 CRISP1,304
 CRISP2,12024
 CRISP3,16904
 CRTC1,16062
 CRTC2,27301
 CRTC3,26148
+CRYBG1,356
 CSGALNACT1,24290
 CSGALNACT2,24292
 CSNK1A1,2451
@@ -735,7 +766,11 @@ CYBB,2578
 CYC1,2579
 DAG1,2666
 DAP3,2673
+DAPK1,2674
+DAPK2,2675
+DAPK3,2676
 DBT,2698
+DCK,2704
 DCN,2705
 DCTN2,2712
 DDR1,2730
@@ -751,12 +786,14 @@ DGKI,2855
 DGKK,32395
 DGKQ,2856
 DGKZ,2857
+DGUOK,2858
 DHH,2865
 DHX58,29517
 DLAT,2896
 DLD,2898
 DMD,2928
 DNM1,2972
+DNM1L,2973
 DNM2,2974
 DNM3,29125
 DPM1,3005
@@ -809,6 +846,14 @@ EDN1,3176
 EDN2,3177
 EDN3,3178
 EED,3188
+EFNA1,3221
+EFNA2,3222
+EFNA3,3223
+EFNA4,3224
+EFNA5,3225
+EFNB1,3226
+EFNB2,3227
+EFNB3,3228
 EGF,3229
 EGFR,3236
 EGR1,3238
@@ -866,6 +911,8 @@ ERCC4,3436
 EREG,3443
 ESR1,3467
 ESR2,3468
+ETNK1,24649
+ETNK2,25575
 ETS1,3488
 ETS2,3489
 EXOC1,30380
@@ -994,6 +1041,7 @@ GABRQ,14454
 GABRR1,4090
 GABRR2,4091
 GABRR3,17969
+GAL,4114
 GALNT1,4123
 GALNT10,19873
 GALNT11,19875
@@ -1014,6 +1062,8 @@ GALNT8,4130
 GALNT9,4131
 GALNTL5,21725
 GALNTL6,33844
+GALP,24840
+GAST,4164
 GATA1,4170
 GATA2,4171
 GATA3,4172
@@ -1033,6 +1083,9 @@ GDF3,4218
 GDF5,4220
 GDF6,4221
 GDF7,4222
+GHRH,4265
+GHRL,18129
+GIP,4270
 GJA1,4274
 GJA10,16995
 GJA3,4277
@@ -1096,6 +1149,8 @@ GNG7,4410
 GNG8,19664
 GNGT1,4411
 GNGT2,4412
+GNRH1,4419
+GNRH2,4420
 GP1BA,4439
 GP1BB,4440
 GP5,4443
@@ -1142,6 +1197,7 @@ GRM5,4597
 GRM6,4598
 GRM7,4599
 GRM8,4600
+GRP,4605
 GSK3A,4616
 GSK3B,4617
 GSTA1,4626
@@ -1250,6 +1306,7 @@ HCN1,4845
 HCN2,4846
 HCN3,19183
 HCN4,16882
+HCRT,4847
 HDAC1,4852
 HDAC10,18128
 HDAC11,19086
@@ -1311,6 +1368,7 @@ HTR3E,24005
 HUS1,5309
 HVCN1,28240
 HYOU1,16931
+IAPP,5329
 IFIH1,18873
 IFNA1,5417
 IFNA10,5418
@@ -1331,7 +1389,9 @@ IFNGR2,5440
 IFNK,21714
 IFNW1,5448
 IFT22,21895
+IGF1,5464
 IGF1R,5465
+IGF2,5466
 IGFBP1,5469
 IGFBP2,5471
 IGFBP3,5472
@@ -1504,6 +1564,7 @@ KIF9,16666
 KIFC1,6389
 KIFC2,29530
 KIFC3,6326
+KISS1,6341
 KLK1,6357
 KLK10,6358
 KLK11,6359
@@ -1520,6 +1581,7 @@ KLK7,6368
 KLK8,6369
 KLK9,6370
 KLKB1,6371
+KNG1,6383
 KRAS,6407
 KSR1,6465
 KSR2,18610
@@ -1536,6 +1598,7 @@ LDHA,6535
 LDHB,6541
 LDHC,6544
 LEF1,6551
+LEP,6553
 LFNG,6560
 LHB,6584
 LPAR1,3166
@@ -1611,12 +1674,35 @@ MCOLN1,13356
 MCOLN2,13357
 MCOLN3,13358
 MED1,9234
+MED10,28760
+MED11,32687
+MED12,11957
+MED12L,16050
+MED13,22474
+MED13L,22962
 MED14,2370
+MED15,14248
+MED16,17556
 MED17,2375
+MED18,25944
+MED19,29600
+MED20,16840
+MED21,11473
+MED22,11477
 MED23,2372
+MED24,22963
+MED25,28845
 MED26,2376
 MED27,2377
+MED28,24628
+MED29,23074
+MED30,23032
+MED31,24260
+MED4,17903
+MED6,19970
 MED7,2378
+MED8,19971
+MED9,25487
 MEF2A,6993
 MEF2B,6995
 MEF2C,6996
@@ -1643,6 +1729,7 @@ MKI67,7107
 MKNK1,7110
 MKNK2,7111
 MKX,23729
+MLN,7141
 MLST8,24825
 MMP1,7155
 MMP10,7156
@@ -1667,6 +1754,13 @@ MMP3,7173
 MMP7,7174
 MMP8,7175
 MMP9,7176
+MOB1A,16015
+MOB1B,29801
+MOB2,24904
+MOB3A,29802
+MOB3B,23825
+MOB3C,29800
+MOB4,17261
 MRPL1,14275
 MRPL10,14055
 MRPL11,14042
@@ -1899,6 +1993,8 @@ NFYB,7805
 NFYC,7806
 NKD1,17045
 NKD2,17046
+NMS,32203
+NMU,7859
 NOS1,7872
 NOS2,7873
 NOS3,7876
@@ -1910,8 +2006,10 @@ NOX1,7889
 NOX3,7890
 NOX4,7891
 NOX5,14874
+NPB,30099
 NPBWR1,4522
 NPBWR2,4530
+NPFF,7901
 NPFFR1,17425
 NPFFR2,4525
 NPPA,7939
@@ -1919,7 +2017,11 @@ NPPB,7940
 NPPC,7941
 NPR1,7943
 NPR2,7944
+NPS,33940
 NPSR1,23631
+NPVF,13782
+NPW,30509
+NPY,7955
 NPY1R,7956
 NPY2R,7957
 NPY4R,9329
@@ -1939,6 +2041,7 @@ NRXN3,8010
 NTRK1,8031
 NTRK2,8032
 NTRK3,8033
+NTS,8038
 NYX,8082
 OGN,8126
 OGT,8127
@@ -2353,6 +2456,7 @@ OR9I1,14718
 OR9K2,15339
 OR9Q1,14724
 OR9Q2,15328
+OXT,8528
 P2RX1,8533
 P2RX2,15459
 P2RX3,8534
@@ -2439,6 +2543,8 @@ PDK1,8809
 PDK2,8810
 PDK3,8811
 PDK4,8812
+PDYN,8820
+PENK,8831
 PF4,8861
 PFN1,8881
 PFN2,8882
@@ -2454,6 +2560,8 @@ PHKA2,8926
 PHKB,8927
 PHKG1,8930
 PHKG2,8931
+PI4KA,8983
+PI4KB,8984
 PIGA,8957
 PIGB,8959
 PIGK,8965
@@ -2518,6 +2626,8 @@ PLD6,30447
 PLPP1,9228
 PLPP2,9230
 PLPP3,9229
+PMCH,9109
+PNOC,9163
 PODN,23174
 PODNL1,26275
 POFUT1,14988
@@ -2546,6 +2656,7 @@ POLR2J,9197
 POLR2J2,23208
 POLR2K,9198
 POLR2L,9199
+POMC,9201
 POMGNT1,19139
 POMGNT2,25902
 POMT1,9202
@@ -2621,6 +2732,7 @@ PPP3CC,9316
 PPP3R1,9317
 PPP3R2,9318
 PPWD1,28954
+PPY,9327
 PRDX1,9352
 PRDX2,9353
 PRDX3,9354
@@ -2654,6 +2766,8 @@ PRKCZ,9412
 PRKD3,9408
 PRKG1,9414
 PRKG2,9416
+PRL,9445
+PRLH,17945
 PRTN3,9495
 PSEN1,9508
 PSEN2,9509
@@ -2706,11 +2820,13 @@ PTGER1,9593
 PTGER2,9594
 PTGER3,9595
 PTGER4,9596
+PTHLH,9607
 PTPA,9308
 PTX3,9692
 PYGB,9723
 PYGL,9725
 PYGM,9726
+PYY,9748
 RAB10,9759
 RAB11A,9760
 RAB11B,9761
@@ -2844,7 +2960,13 @@ RHOC,669
 RHOG,672
 RICTOR,28611
 RING1,10018
+RIPK1,10019
+RIPK2,10020
+RLN1,10026
+RLN2,10027
+RLN3,17135
 RNF2,10061
+RNH1,10074
 ROBO1,10249
 ROBO2,10250
 ROBO3,13433
@@ -2922,6 +3044,7 @@ SCNN1A,10599
 SCNN1B,10600
 SCNN1D,10601
 SCNN1G,10602
+SCT,10607
 SDHA,10680
 SDHB,10681
 SDHC,10682
@@ -2977,6 +3100,7 @@ SLC2A6,11011
 SLC2A7,13445
 SLC2A8,13812
 SLC2A9,13446
+SLK,11088
 SLX4,23845
 SMAD1,6767
 SMAD2,6768
@@ -3016,6 +3140,7 @@ SOD3,11181
 SOS1,11187
 SOS2,11188
 SPHK1,11240
+SPHK2,18859
 SPRED1,20249
 SPRED2,17722
 SPRED3,31041
@@ -3027,6 +3152,7 @@ SRC,11283
 SREBF1,11289
 SREBF2,11290
 SSPN,11322
+SST,11329
 ST3GAL1,10862
 ST3GAL2,10863
 ST3GAL3,10866
@@ -3056,11 +3182,16 @@ STAT4,11365
 STAT5A,11366
 STAT5B,11367
 STAT6,11368
+STK17A,11395
+STK17B,11396
 STT3A,6172
 STT3B,30611
 SUGT1,16987
 SUMO3,11124
 SUZ12,17101
+TAC1,11517
+TAC3,11521
+TAC4,16641
 TAF1A,11532
 TAF1B,11533
 TAF1C,11534
@@ -3095,6 +3226,7 @@ TGFB3,11769
 TGFBR1,11772
 TGFBR2,11773
 TGFBR3,11774
+THAP12,9440
 THBS1,11785
 THBS2,11786
 THBS3,11787
@@ -3104,6 +3236,8 @@ THRB,11799
 TIAM1,11805
 TIAM2,11806
 TIPARP,23696
+TK1,11830
+TK2,11831
 TLR1,11847
 TLR10,15634
 TLR2,11848
@@ -3148,8 +3282,12 @@ TNNT2,11949
 TNNT3,11950
 TNR,11953
 TNXB,11976
+TOP1,11986
+TOP1MT,29787
 TOP2A,11989
 TOP2B,11990
+TOP3A,11992
+TOP3B,11993
 TP53,11998
 TP63,15979
 TP73,12003
@@ -3164,6 +3302,7 @@ TRAP1,16264
 TRB,12155
 TRD,12252
 TRG,12271
+TRH,12298
 TRIM23,660
 TRPA1,497
 TRPC1,12333
@@ -3247,6 +3386,9 @@ UBE2T,25009
 UBE2V1,12494
 UBE2V2,12495
 UBE2W,25616
+UCN,12516
+UCN2,18414
+UCN3,17781
 UGCG,12524
 UGGT1,15663
 UGGT2,15664
@@ -3292,6 +3434,7 @@ UQCRH,12590
 UQCRQ,29594
 USP5,12628
 UTRN,12635
+UTS2,12636
 VAV1,12657
 VAV2,12658
 VAV3,12659
@@ -3302,6 +3445,7 @@ VEGFA,12680
 VEGFB,12681
 VEGFC,12682
 VEGFD,3708
+VIP,12693
 VPS51,1172
 VPS52,10518
 VPS53,25608
@@ -3345,5 +3489,6 @@ YWHAQ,12854
 YWHAZ,12855
 YY1,12856
 ZACN,29504
+ZAP70,12858
 ZNF134,12918
 ZW10,13194
diff --git a/grounding_map.csv b/grounding_map.csv
index f7679498d..a6252873e 100644
--- a/grounding_map.csv
+++ b/grounding_map.csv
@@ -438,17 +438,17 @@ calcium channel,FPLX,Calcium_channels,,,,
 calcium channels,FPLX,Calcium_channels,,,,
 Calmodulin,FPLX,CALM,,,,
 calmodulin,FPLX,CALM,,,,
-calmodulindependent kinase II,FPLX,CAMK2_family,,,,
+calmodulindependent kinase II,FPLX,CAMK2_complex,,,,
 calpain,FPLX,CAPN,,,,
 CaM kinase II,FPLX,CAMK2_complex,,,,
 CaM,FPLX,CALM,,,,
 CaMK family,FPLX,CAMK,,,,
 CaMK II,FPLX,CAMK2_complex,,,,
 CaMK,FPLX,CAMK,,,,
-CAMK2,FPLX,CAMK2_family,,,,
-CaMK2,FPLX,CAMK2_family,,,,
+CAMK2,FPLX,CAMK2_complex,,,,
+CaMK2,FPLX,CAMK2_complex,,,,
 CaMKII,FPLX,CAMK2_complex,,,,
-CAMKII,FPLX,CAMK2_family,,,,
+CAMKII,FPLX,CAMK2_complex,,,,
 cAMP,PUBCHEM,6076,CHEBI,CHEBI:17489,HMDB,HMDB00058
 cAMP-dependent PK,FPLX,PKA,,,,
 cAMP-dependent protein kinase,FPLX,PKA,,,,
@@ -576,7 +576,6 @@ CIP2A,UP,Q8TCG1,,,,
 Cisplatin,CHEBI,CHEBI:27899,PUBCHEM,441203,,
 cisplatin,CHEBI,CHEBI:27899,PUBCHEM,441203,,
 CK2,FPLX,CK2,,,,
-CKI,FPLX,CDKN,,,,
 Clade B serpin,FPLX,SERPINB,,,,
 clade B serpins,FPLX,SERPINB,,,,
 Class 1 NF-kappaBs,FPLX,NFkappaB_1,,,,
@@ -1197,7 +1196,7 @@ hTERT,UP,O14746,,,,
 HuR,HGNC,ELAVL1,UP,Q15717,,
 hydrogen peroxide,PUBCHEM,784,CHEBI,CHEBI:16240,,
 hypoxia-inducible factors,FPLX,HIF,,,,
-I/R,MESH,D011839,,,,
+I/R,MESH,D015427,,,,
 ICAM-1,UP,P05362,,,,
 IER3,UP,P46695,,,,
 IFI16,UP,Q16666,,,,
@@ -1227,13 +1226,13 @@ IGF1,UP,P05019,,,,
 IGF1R,UP,P08069,,,,
 IGFBP,FPLX,IGFBP,,,,
 IGFBPs,FPLX,IGFBP,,,,
-IkappaB kinase,FPLX,IKK_family,,,,
+IkappaB kinase,FPLX,IKK_complex,,,,
 IkappaB,FPLX,IKB,,,,
 IkappaB-alpha,HGNC,NFKBIA,,,,
 IkappaBalpha,UP,P25963,,,,
 IK1,FPLX,KCNJ,,,,
 IKK complex,FPLX,IKK_complex,,,,
-IKK,FPLX,IKK_family,,,,
+IKK,FPLX,IKK_complex,,,,
 IKKalpha,UP,O15111,,,,
 IKKbeta,UP,O14920,,,,
 IKKβ,UP,O14920,,,,
@@ -1308,7 +1307,7 @@ IRS1,UP,P35568,,,,
 IRS2,UP,Q9Y4H2,,,,
 ischemia,MESH,D007511,,,,
 isoflurane,PUBCHEM,3763,CHEBI,CHEBI:6015,,
-IκB kinase,FPLX,IKK_family,,,,
+IκB kinase,FPLX,IKK_complex,,,,
 IκB,FPLX,IKB,,,,
 IκB-α,HGNC,NFKBIA,,,,
 IκBα,UP,P25963,,,,
@@ -1403,7 +1402,7 @@ MAP3K2,UP,Q9Y2U5,,,,
 MAPK kinase kinase,FPLX,MAP3K,,,,
 MAPK kinase,FPLX,MAP2K,,,,
 MAPK p38,FPLX,p38,,,,
-MAPK,FPLX,ERK,,,,
+MAPK,FPLX,MAPK,,,,
 MAPK1,UP,P28482,,,,
 MAPK3,UP,P27361,,,,
 MAPKK kinases,FPLX,MAP3K,,,,
@@ -2248,6 +2247,7 @@ senescence,GO,GO:0090398,MESH,D016922,,
 SERCA,FPLX,SERCA,,,,
 SERCAs,FPLX,SERCA,,,,
 SFK,FPLX,SRC,,,,
+SFKs,FPLX,SRC,,,,
 SFN,CHEBI,CHEBI:47807,PUBCHEM,5350,,
 Shc family,FPLX,SHC,,,,
 SHC,FPLX,SHC,,,,
@@ -2321,6 +2321,7 @@ Src family,FPLX,SRC,,,,
 src kinases,FPLX,SRC,,,,
 SRC,UP,P12931,,,,
 Src,UP,P12931,,,,
+Src kinase,UP,P12931,,,,
 SRC-family kinases,FPLX,SRC,,,,
 Src-kinases,FPLX,SRC,,,,
 SREBF family,FPLX,SREBF,,,,
@@ -2689,7 +2690,7 @@ MNK,HGNC,ATP7A,,,,
 Mnk,HGNC,ATP7A,,,,
 MNK,FPLX,MKNK,,,,
 Mnk,FPLX,MKNK,,,,
-CaM serine/threonine kinase II,FPLX,CAMK2_family,,,,
+CaM serine/threonine kinase II,FPLX,CAMK2_complex,,,,
 PCTAIRE,HGNC,CDK16,,,,
 SLE,MESH,D008180,,,,
 NIK,HGNC,MAP3K14,,,,
@@ -2701,6 +2702,7 @@ p42(mapk) and p44(mapk),FPLX,ERK,,,,
 p42 and p38 MAPK,FPLX,ERK,,,,
 p42 and p38 MAP kinases,FPLX,ERK,,,,
 p42 and p38 MAPKs,FPLX,ERK,,,,
+p42/44,FPLX,ERK,,,,
 thiazolidinediones,MESH,D045162,CHEBI,CHEBI:50990,,
 TRAP,UP,P16893,,,,
 ERK4,HGNC,MAPK4,,,,
@@ -2737,3 +2739,125 @@ neuropeptide FF receptor,FPLX,NPFFR,,,,
 neuropeptide FF receptors,FPLX,NPFFR,,,,
 neuropeptide Y receptor,FPLX,NPYR,,,,
 neuropeptide Y receptors,FPLX,NPYR,,,,
+creatine,CHEBI,CHEBI:16919,,,,
+SAPK,FPLX,JNK,,,,
+s6k,FPLX,P70S6K,,,,
+growth factor receptor,NCIT,C17664,,,,
+growth factor receptors,NCIT,C17664,,,,
+derived growth factor,FPLX,PDGFR,,,,
+PDGF receptors,FPLX,PDGFR,,,,
+creatine kinase,FPLX,Creatine_kinase,,,,
+ephrin,FPLX,EFN,,,,
+ephrins,FPLX,EFN,,,,
+phosphatidylinositol 4-kinase,FPLX,PI4K,,,,
+PI4K,FPLX,PI4K,,,,
+DAPK,FPLX,DAPK,,,,
+DAPk,FPLX,DAPK,,,,
+Sphingosine kinase,FPLX,SPHK,,,,
+sphingosine kinase,FPLX,SPHK,,,,
+SphK,FPLX,SPHK,,,,
+SAT,MESH,D050151,,,,
+topoisomerase,FPLX,TOP,,,,
+AIM1,HGNC,CRYBG1,,,,
+Clk,HGNC,CLOCK,,,,
+TraD,UP,P09130,,,,
+SK2,HGNC,KCNN2,,,,
+AMP-activated,FPLX,AMPK,,,,
+oxidant,MESH,D016877,,,,
+Ste20,UP,Q03497,,,,
+Ste20-like kinase,HGNC,SLK,,,,
+chk,FPLX,CHK,,,,
+ethanolamine kinase,FPLX,CHK,,,,
+Chaetoglobosin K,PUBCHEM,5477706,,,,
+CKIs,FPLX,CDKN,,,,
+choline kinase,FPLX,CHK,,,,
+EphB receptor,FPLX,EPHB,,,,
+p-38,FPLX,p38,,,,
+p38 SAPK,FPLX,p38,,,,
+GPR,IP,IPR000965,,,,
+BVR,FPLX,BLVR,,,,
+Ir,CHEBI,CHEBI:49666,,,,
+Hep,CHEBI,CHEBI:28304,,,,
+phosphoinositide 3-kinase,FPLX,PI3K,,,,
+I-R,MESH,D015427,,,,
+aura,MESH,D020325,,,,
+CCK-4,CHEBI,CHEBI:137728,,,,
+Ach,CHEBI,CHEBI:15355,,,,
+BcR,MESH,D011947,,,,
+cAK,FPLX,PRKAC,,,,
+Drp-1,HGNC,DNM1L,,,,
+phosphoinositide-3 kinase,FPLX,PI3K,,,,
+brk,UP,Q9XTN4,,,,
+Ischemia-reperfusion,MESH,D015427,,,,
+Phosphoinositide 3-kinase,FPLX,PI3K,,,,
+rSK2,HGNC,KCNN2,,,,
+Dgk,FPLX,DGK,,,,
+AcH,CHEBI,CHEBI:15343,,,,
+dCAF-1,UP,Q24572,,,,
+hRI,HGNC,RNH1,,,,
+Mhc,FPLX,MYH,,,,
+Cdkn1,FPLX,CDKN1,,,,
+cerebral ischemia-reperfusion,MESH,D015427,,,,
+Iterative reconstruction,NCIT,C94918,,,,
+raf protein,FPLX,RAF,,,,
+biochemical recurrence,NCIT,C93229,,,,
+Bsk,UP,P92208,,,,
+StAR,HGNC,STAR,,,,
+StaR,HGNC,STAR,,,,
+STAR,HGNC,STAR,,,,
+Star,HGNC,STAR,,,,
+pLK,CHEBI,CHEBI:53412,,,,
+tyrosine kinase receptor,MESH,D020794,,,,
+rSK1,HGNC,KCNN1,,,,
+glycogen,CHEBI,CHEBI:28087,,,,
+mK3,UP,O41933,,,,
+deoxycytidine,CHEBI,CHEBI:15698,,,,
+SP600125,CHEBI,CHEBI:90695,,,,
+p94,HGNC,CAPN3,,,,
+ros1,UP,Q9SJQ6,,,,
+Frp1,UP,Q6B957,,,,
+FRP-1,MESH,D027261,,,,
+Nak,UP,Q9U485,,,,
+hK4,HGNC,KLK4,,,,
+NprB,UP,A0A0J6R5F8,,,,
+gK,UP,P68331,,,,
+CAMK-II,FPLX,CAMK2_complex,,,,
+dTK,FPLX,TK,,,,
+PKA C-alpha,FPLX,PRKAC,,,,
+rac,FPLX,RAC,,,,
+SRC-1,HGNC,NCOA1,,,,
+CaMKII protein,FPLX,CAMK2_complex,,,,
+her4,UP,Q90466,,,,
+Ert1,UP,P38140,,,,
+galK,UP,P0A6T3,,,,
+rIPK,HGNC,THAP12,,,,
+hER,FPLX,ESR,,,,
+Rac,FPLX,RAC,,,,
+endoribonuclease,NCIT,C25959,,,,
+nprB,UP,A0A0J6R5F8,,,,
+SRC1,HGNC,NCOA1,,,,
+Src-homology,MESH,D018909,,,,
+Src-1,HGNC,NCOA1,,,,
+CAMK,FPLX,CAMK,,,,
+RIPK,FPLX,RIPK,,,,
+CAM-KII,FPLX,CAMK2_complex,,,,
+p-CaMKII,FPLX,CAMK2_complex,,,,
+CaMK-II,FPLX,CAMK2_complex,,,,
+RAc,CHEBI,CHEBI:17336,,,,
+ZAP-70,HGNC,ZAP70,,,,
+GCa,MESH,D013274,,,,
+ssk1,UP,Q07084,,,,
+CK-I,FPLX,CSNK1,,,,
+Chkl,HGNC,CHEK1,,,,
+pEK,HGNC,PENK,,,,
+SEK,HGNC,MAP2K4,,,,
+neutrophils,MESH,D009504,,,,
+Neutrophils,MESH,D009504,,,,
+Ly49D,UP,Q60651,,,,
+NF-kappaB-inducing kinase,HGNC,MAP3K14,,,,
+p38b,HGNC,MAPK11,,,,
+cSBP,MESH,D001794,,,,
+pfkA,UP,P0A796,,,,
+Pka1,UP,P06244,,,,
+uridine,CHEBI,CHEBI:16704,HMDB,HMDB0000296,,
+Uridine,CHEBI,CHEBI:16704,HMDB,HMDB0000296,,
diff --git a/import/hgnc_families.py b/import/hgnc_families.py
index 700ed8234..f9551c00a 100644
--- a/import/hgnc_families.py
+++ b/import/hgnc_families.py
@@ -88,18 +88,17 @@ def get_relations_from_root(root_id, relations=None):
     child_ids = children.get(root_id)
     famplex_id = get_famplex_id(family_info)
     # In this case this HGNC family has genes as its children
-    if not child_ids:
-        gene_members = family_to_gene[root_id]
-        for gene in gene_members:
-            gene_name = hgnc_client.get_hgnc_name(gene)
-            if is_pseudogene(gene_name):
-                print('Assuming %s is a pseudogene, skipping' % gene_name)
-                continue
-            rel = ('HGNC', gene_name, 'isa', 'FPLX', famplex_id, root_id)
-            relations.append(rel)
+    gene_members = family_to_gene[root_id]
+    for gene in gene_members:
+        gene_name = hgnc_client.get_hgnc_name(gene)
+        if is_pseudogene(gene_name):
+            print('Assuming %s is a pseudogene, skipping' % gene_name)
+            continue
+        rel = ('HGNC', gene_name, 'isa', 'FPLX', famplex_id, root_id)
+        relations.append(rel)
     # In this case this HGNC family is an intermediate that has further
     # families as its children
-    else:
+    if child_ids is not None:
         for child_id in child_ids:
             # We want to skip families that only consist of a single gene,
             # and therefore these genes are directly linked to their
diff --git a/relations.csv b/relations.csv
index ebf95a045..10235375d 100644
--- a/relations.csv
+++ b/relations.csv
@@ -1097,9 +1097,6 @@ HGNC,E2F5,isa,FPLX,E2F
 HGNC,E2F6,isa,FPLX,E2F
 HGNC,E2F7,isa,FPLX,E2F
 HGNC,E2F8,isa,FPLX,E2F
-HGNC,EDN1,isa,FPLX,EDN
-HGNC,EDN2,isa,FPLX,EDN
-HGNC,EDN3,isa,FPLX,EDN
 HGNC,AREG,isa,FPLX,EGFR_ligand
 HGNC,EGF,isa,FPLX,EGFR_ligand
 HGNC,TGFA,isa,FPLX,EGFR_ligand
@@ -1133,20 +1130,22 @@ HGNC,ENO1,isa,FPLX,ENO
 HGNC,ENO2,isa,FPLX,ENO
 HGNC,ENO3,isa,FPLX,ENO
 HGNC,ENO4,isa,FPLX,ENO
-HGNC,EPHA1,isa,FPLX,Ephrin_receptor
-HGNC,EPHA2,isa,FPLX,Ephrin_receptor
-HGNC,EPHA3,isa,FPLX,Ephrin_receptor
-HGNC,EPHA4,isa,FPLX,Ephrin_receptor
-HGNC,EPHA5,isa,FPLX,Ephrin_receptor
-HGNC,EPHA6,isa,FPLX,Ephrin_receptor
-HGNC,EPHA7,isa,FPLX,Ephrin_receptor
-HGNC,EPHA8,isa,FPLX,Ephrin_receptor
-HGNC,EPHB1,isa,FPLX,Ephrin_receptor
-HGNC,EPHB2,isa,FPLX,Ephrin_receptor
-HGNC,EPHB3,isa,FPLX,Ephrin_receptor
-HGNC,EPHB4,isa,FPLX,Ephrin_receptor
-HGNC,EPHB6,isa,FPLX,Ephrin_receptor
-HGNC,EPHA10,isa,FPLX,Ephrin_receptor
+HGNC,EPHA1,isa,FPLX,EPHA
+HGNC,EPHA2,isa,FPLX,EPHA
+HGNC,EPHA3,isa,FPLX,EPHA
+HGNC,EPHA4,isa,FPLX,EPHA
+HGNC,EPHA5,isa,FPLX,EPHA
+HGNC,EPHA6,isa,FPLX,EPHA
+HGNC,EPHA7,isa,FPLX,EPHA
+HGNC,EPHA8,isa,FPLX,EPHA
+HGNC,EPHA10,isa,FPLX,EPHA
+HGNC,EPHB1,isa,FPLX,EPHB
+HGNC,EPHB2,isa,FPLX,EPHB
+HGNC,EPHB3,isa,FPLX,EPHB
+HGNC,EPHB4,isa,FPLX,EPHB
+HGNC,EPHB6,isa,FPLX,EPHB
+FPLX,EPHA,isa,FPLX,Ephrin_receptor
+FPLX,EPHB,isa,FPLX,Ephrin_receptor
 HGNC,EPN1,isa,FPLX,EPN
 HGNC,EPN2,isa,FPLX,EPN
 HGNC,EPN3,isa,FPLX,EPN
@@ -3725,3 +3724,174 @@ HGNC,VPS51,partof,FPLX,GARP
 HGNC,VPS52,partof,FPLX,GARP
 HGNC,VPS53,partof,FPLX,GARP
 HGNC,VPS54,partof,FPLX,GARP
+HGNC,CCNC,partof,FPLX,MED
+HGNC,CDK8,partof,FPLX,MED
+HGNC,CDK19,partof,FPLX,MED
+HGNC,MED1,partof,FPLX,MED
+HGNC,MED29,partof,FPLX,MED
+HGNC,MED27,partof,FPLX,MED
+HGNC,MED4,partof,FPLX,MED
+HGNC,MED24,partof,FPLX,MED
+HGNC,MED6,partof,FPLX,MED
+HGNC,MED7,partof,FPLX,MED
+HGNC,MED8,partof,FPLX,MED
+HGNC,MED9,partof,FPLX,MED
+HGNC,MED10,partof,FPLX,MED
+HGNC,MED11,partof,FPLX,MED
+HGNC,MED12,partof,FPLX,MED
+HGNC,MED12L,partof,FPLX,MED
+HGNC,MED13,partof,FPLX,MED
+HGNC,MED13L,partof,FPLX,MED
+HGNC,MED14,partof,FPLX,MED
+HGNC,MED15,partof,FPLX,MED
+HGNC,MED16,partof,FPLX,MED
+HGNC,MED17,partof,FPLX,MED
+HGNC,MED18,partof,FPLX,MED
+HGNC,MED19,partof,FPLX,MED
+HGNC,MED20,partof,FPLX,MED
+HGNC,MED21,partof,FPLX,MED
+HGNC,MED22,partof,FPLX,MED
+HGNC,MED23,partof,FPLX,MED
+HGNC,MED25,partof,FPLX,MED
+HGNC,MED26,partof,FPLX,MED
+HGNC,MED28,partof,FPLX,MED
+HGNC,MED30,partof,FPLX,MED
+HGNC,MED31,partof,FPLX,MED
+FPLX,RSTK1,isa,FPLX,RSTK
+FPLX,RSTK2,isa,FPLX,RSTK
+HGNC,ACVRL1,isa,FPLX,RSTK1
+HGNC,ACVR1,isa,FPLX,RSTK1
+HGNC,ACVR1B,isa,FPLX,RSTK1
+HGNC,ACVR1C,isa,FPLX,RSTK1
+HGNC,BMPR1A,isa,FPLX,RSTK1
+HGNC,BMPR1B,isa,FPLX,RSTK1
+HGNC,TGFBR1,isa,FPLX,RSTK1
+HGNC,ACVR2A,isa,FPLX,RSTK2
+HGNC,ACVR2B,isa,FPLX,RSTK2
+HGNC,AMHR2,isa,FPLX,RSTK2
+HGNC,BMPR2,isa,FPLX,RSTK2
+HGNC,TGFBR2,isa,FPLX,RSTK2
+HGNC,CDK9,partof,FPLX,TAT_associated_kinase
+HGNC,CCNT1,partof,FPLX,TAT_associated_kinase
+HGNC,CKB,isa,FPLX,Creatine_kinase
+HGNC,CKBE,isa,FPLX,Creatine_kinase
+HGNC,CKM,isa,FPLX,Creatine_kinase
+HGNC,CKMT1A,isa,FPLX,Creatine_kinase
+HGNC,CKMT1B,isa,FPLX,Creatine_kinase
+HGNC,CKMT2,isa,FPLX,Creatine_kinase
+HGNC,EFNA1,isa,FPLX,EFN
+HGNC,EFNA2,isa,FPLX,EFN
+HGNC,EFNA3,isa,FPLX,EFN
+HGNC,EFNA4,isa,FPLX,EFN
+HGNC,EFNA5,isa,FPLX,EFN
+HGNC,EFNB1,isa,FPLX,EFN
+HGNC,EFNB2,isa,FPLX,EFN
+HGNC,EFNB3,isa,FPLX,EFN
+HGNC,PI4KA,isa,FPLX,PI4K
+HGNC,PI4KB,isa,FPLX,PI4K
+HGNC,DAPK1,isa,FPLX,DAPK
+HGNC,DAPK2,isa,FPLX,DAPK
+HGNC,DAPK3,isa,FPLX,DAPK
+HGNC,STK17A,isa,FPLX,DAPK
+HGNC,STK17B,isa,FPLX,DAPK
+HGNC,MOB1A,isa,FPLX,MOB
+HGNC,MOB1B,isa,FPLX,MOB
+HGNC,MOB2,isa,FPLX,MOB
+HGNC,MOB3A,isa,FPLX,MOB
+HGNC,MOB3B,isa,FPLX,MOB
+HGNC,MOB3C,isa,FPLX,MOB
+HGNC,MOB4,isa,FPLX,MOB
+HGNC,SPHK1,isa,FPLX,SPHK
+HGNC,SPHK2,isa,FPLX,SPHK
+HGNC,TOP1,isa,FPLX,TOP
+HGNC,TOP1MT,isa,FPLX,TOP
+FPLX,TOP2,isa,FPLX,TOP
+HGNC,TOP3A,isa,FPLX,TOP
+HGNC,TOP3B,isa,FPLX,TOP
+HGNC,CHKA,isa,FPLX,CHK
+HGNC,CHKB,isa,FPLX,CHK
+HGNC,EDN1,isa,FPLX,EDN
+HGNC,EDN2,isa,FPLX,EDN
+HGNC,EDN3,isa,FPLX,EDN
+HGNC,ADCYAP1,isa,FPLX,Neuropeptides
+HGNC,ADM,isa,FPLX,Neuropeptides
+HGNC,ADM2,isa,FPLX,Neuropeptides
+HGNC,AGRP,isa,FPLX,Neuropeptides
+HGNC,AGT,isa,FPLX,Neuropeptides
+HGNC,APLN,isa,FPLX,Neuropeptides
+HGNC,AVP,isa,FPLX,Neuropeptides
+HGNC,CALCA,isa,FPLX,Neuropeptides
+HGNC,CALCB,isa,FPLX,Neuropeptides
+HGNC,CCK,isa,FPLX,Neuropeptides
+HGNC,CHGA,isa,FPLX,Neuropeptides
+HGNC,CRH,isa,FPLX,Neuropeptides
+FPLX,EDN,isa,FPLX,Neuropeptides
+HGNC,GAL,isa,FPLX,Neuropeptides
+HGNC,GALP,isa,FPLX,Neuropeptides
+HGNC,GAST,isa,FPLX,Neuropeptides
+HGNC,GHRH,isa,FPLX,Neuropeptides
+HGNC,GHRL,isa,FPLX,Neuropeptides
+HGNC,GIP,isa,FPLX,Neuropeptides
+HGNC,GNRH1,isa,FPLX,Neuropeptides
+HGNC,GNRH2,isa,FPLX,Neuropeptides
+HGNC,GRP,isa,FPLX,Neuropeptides
+HGNC,HCRT,isa,FPLX,Neuropeptides
+HGNC,IAPP,isa,FPLX,Neuropeptides
+HGNC,IGF1,isa,FPLX,Neuropeptides
+HGNC,IGF2,isa,FPLX,Neuropeptides
+HGNC,INS,isa,FPLX,Neuropeptides
+HGNC,KISS1,isa,FPLX,Neuropeptides
+HGNC,KNG1,isa,FPLX,Neuropeptides
+HGNC,LEP,isa,FPLX,Neuropeptides
+HGNC,MLN,isa,FPLX,Neuropeptides
+HGNC,NMS,isa,FPLX,Neuropeptides
+HGNC,NMU,isa,FPLX,Neuropeptides
+HGNC,NPB,isa,FPLX,Neuropeptides
+HGNC,NPFF,isa,FPLX,Neuropeptides
+HGNC,NPS,isa,FPLX,Neuropeptides
+HGNC,NPVF,isa,FPLX,Neuropeptides
+HGNC,NPW,isa,FPLX,Neuropeptides
+HGNC,NPY,isa,FPLX,Neuropeptides
+HGNC,NTS,isa,FPLX,Neuropeptides
+HGNC,OXT,isa,FPLX,Neuropeptides
+HGNC,PDYN,isa,FPLX,Neuropeptides
+HGNC,PENK,isa,FPLX,Neuropeptides
+HGNC,PMCH,isa,FPLX,Neuropeptides
+HGNC,PNOC,isa,FPLX,Neuropeptides
+HGNC,POMC,isa,FPLX,Neuropeptides
+HGNC,PPY,isa,FPLX,Neuropeptides
+HGNC,PRL,isa,FPLX,Neuropeptides
+HGNC,PRLH,isa,FPLX,Neuropeptides
+HGNC,PTHLH,isa,FPLX,Neuropeptides
+HGNC,PYY,isa,FPLX,Neuropeptides
+HGNC,RLN1,isa,FPLX,Neuropeptides
+HGNC,RLN2,isa,FPLX,Neuropeptides
+HGNC,RLN3,isa,FPLX,Neuropeptides
+HGNC,SCT,isa,FPLX,Neuropeptides
+HGNC,SST,isa,FPLX,Neuropeptides
+FPLX,TAC,isa,FPLX,Neuropeptides
+FPLX,Natriuretic_peptide,isa,FPLX,Neuropeptides
+HGNC,TRH,isa,FPLX,Neuropeptides
+HGNC,UCN,isa,FPLX,Neuropeptides
+HGNC,UCN2,isa,FPLX,Neuropeptides
+HGNC,UCN3,isa,FPLX,Neuropeptides
+HGNC,UTS2,isa,FPLX,Neuropeptides
+HGNC,VIP,isa,FPLX,Neuropeptides
+HGNC,TAC1,isa,FPLX,TAC
+HGNC,TAC3,isa,FPLX,TAC
+HGNC,TAC4,isa,FPLX,TAC
+HGNC,ETNK1,isa,FPLX,ETNK
+HGNC,ETNK2,isa,FPLX,ETNK
+HGNC,CLK1,isa,FPLX,CLK
+HGNC,CLK2,isa,FPLX,CLK
+HGNC,CLK3,isa,FPLX,CLK
+HGNC,CLK4,isa,FPLX,CLK
+HGNC,BLVRA,isa,FPLX,BLVR
+HGNC,BLVRB,isa,FPLX,BLVR
+HGNC,DCK,isa,FPLX,Deoxyribonucleoside_kinases
+HGNC,DGUOK,isa,FPLX,Deoxyribonucleoside_kinases
+FPLX,TK,isa,FPLX,Deoxyribonucleoside_kinases
+HGNC,TK1,isa,FPLX,Deoxyribonucleoside_kinases
+HGNC,TK2,isa,FPLX,Deoxyribonucleoside_kinases
+HGNC,RIPK1,isa,FPLX,RIPK
+HGNC,RIPK2,isa,FPLX,RIPK