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Row category based on highest cell-type category expression #19

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cornhundred opened this issue Jun 13, 2019 · 0 comments
Open
3 tasks

Row category based on highest cell-type category expression #19

cornhundred opened this issue Jun 13, 2019 · 0 comments
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enhancement New feature or request help wanted Extra attention is needed

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@cornhundred
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cornhundred commented Jun 13, 2019

I have a few examples where we generate gene expression signatures based on some single cell categories (e.g. cell type) and then add gene-level (row) categories based on which cell category the gene is most highly expressed in. This usually only adds categories for a subset of genes since not all genes are considered "signature" genes. We should simplify this process and have the following features:

  • Assign each gene a category based on which cell type (or generally category) it is most highly expressed
  • Calculate this in the front end after setting manual categories
  • Show the P-value (-log10) as a value-based category of the one-vs-all T-test. This allows users to easily identify significantly differentially up-regulated genes in a category
@cornhundred cornhundred added enhancement New feature or request help wanted Extra attention is needed labels Jun 13, 2019
@cornhundred cornhundred self-assigned this Jun 13, 2019
@cornhundred cornhundred changed the title Gene category based on highest cell-type category expression Row category based on highest cell-type category expression May 24, 2020
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enhancement New feature or request help wanted Extra attention is needed
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