diff --git a/gapic/schema/wrappers.py b/gapic/schema/wrappers.py
index 24422244a9..2fbc5a2b20 100644
--- a/gapic/schema/wrappers.py
+++ b/gapic/schema/wrappers.py
@@ -743,6 +743,7 @@ def try_parse_http_rule(cls, http_rule) -> Optional['HttpRule']:
         uri = getattr(http_rule, method)
         if not uri:
             return None
+        uri = utils.convert_uri_fieldnames(uri)
 
         body = http_rule.body or None
         return cls(method, uri, body)
diff --git a/gapic/utils/__init__.py b/gapic/utils/__init__.py
index 447b0df837..5000d78b49 100644
--- a/gapic/utils/__init__.py
+++ b/gapic/utils/__init__.py
@@ -28,11 +28,13 @@
 from gapic.utils.options import Options
 from gapic.utils.reserved_names import RESERVED_NAMES
 from gapic.utils.rst import rst
+from gapic.utils.uri_conv import convert_uri_fieldnames
 from gapic.utils.uri_sample import sample_from_path_fields
 
 
 __all__ = (
     'cached_property',
+    'convert_uri_fieldnames',
     'doc',
     'empty',
     'is_msg_field_pb',
diff --git a/gapic/utils/uri_conv.py b/gapic/utils/uri_conv.py
new file mode 100644
index 0000000000..988a8c2997
--- /dev/null
+++ b/gapic/utils/uri_conv.py
@@ -0,0 +1,49 @@
+# Copyright 2021 Google LLC
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     https://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+from gapic.utils.reserved_names import RESERVED_NAMES
+from google.api_core import path_template  # type: ignore
+
+
+def convert_uri_fieldnames(uri: str) -> str:
+    """Modify field names in uri_templates to avoid reserved names.
+
+    Args:
+        uri: a uri template, optionally containing field references in {} braces.
+
+    Returns:
+        the uri with any field names modified if they conflict with
+        reserved names.
+    """
+
+    def _fix_name_segment(name_seg: str) -> str:
+        return name_seg + "_" if name_seg in RESERVED_NAMES else name_seg
+
+    def _fix_field_path(field_path: str) -> str:
+        return ".".join(
+            (_fix_name_segment(name_seg) for name_seg in field_path.split(".")))
+
+    last = 0
+    pieces = []
+    for match in path_template._VARIABLE_RE.finditer(uri):
+        start_pos, end_pos = match.span("name")
+        if start_pos == end_pos:
+            continue
+        pieces.append(uri[last:start_pos])
+        fixed_field_path = _fix_field_path(uri[start_pos:end_pos])
+        pieces.append(fixed_field_path)
+        last = end_pos
+    pieces.append(uri[last:])
+
+    return "".join(pieces)
diff --git a/noxfile.py b/noxfile.py
index 8b446ff44b..c4e3f34f43 100644
--- a/noxfile.py
+++ b/noxfile.py
@@ -34,7 +34,7 @@ def unit(session):
     """Run the unit test suite."""
 
     session.install(
-        "coverage", "pytest-cov", "pytest", "pytest-xdist", "pyfakefs",
+        "coverage", "pytest-cov", "pytest", "pytest-xdist", "pyfakefs", "grpcio-status",
     )
     session.install("-e", ".")
 
diff --git a/tests/unit/schema/wrappers/test_method.py b/tests/unit/schema/wrappers/test_method.py
index d377375036..72766d453e 100644
--- a/tests/unit/schema/wrappers/test_method.py
+++ b/tests/unit/schema/wrappers/test_method.py
@@ -452,6 +452,19 @@ def test_method_http_options_additional_bindings():
             }]
 
 
+def test_method_http_options_reserved_name_in_url():
+    http_rule = http_pb2.HttpRule(
+        post='/v1/license/{license=lic/*}',
+        body='*'
+    )
+    method = make_method('DoSomething', http_rule=http_rule)
+    assert [dataclasses.asdict(http) for http in method.http_options] == [{
+        'method': 'post',
+        'uri': '/v1/license/{license_=lic/*}',
+        'body': '*'
+    }]
+
+
 def test_method_http_options_generate_sample():
     http_rule = http_pb2.HttpRule(
         get='/v1/{resource.id=projects/*/regions/*/id/**}/stuff',
diff --git a/tests/unit/utils/test_uri_conv.py b/tests/unit/utils/test_uri_conv.py
new file mode 100644
index 0000000000..5c870b430a
--- /dev/null
+++ b/tests/unit/utils/test_uri_conv.py
@@ -0,0 +1,35 @@
+# Copyright 2021 Google LLC
+#
+# Licensed under the Apache License, Version 2.0 (the "License");
+# you may not use this file except in compliance with the License.
+# You may obtain a copy of the License at
+#
+#     https://www.apache.org/licenses/LICENSE-2.0
+#
+# Unless required by applicable law or agreed to in writing, software
+# distributed under the License is distributed on an "AS IS" BASIS,
+# WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+# See the License for the specific language governing permissions and
+# limitations under the License.
+
+from unittest import mock
+
+import pypandoc
+
+from gapic import utils
+
+
+def test_convert_uri_fieldname():
+    uri = "abc/*/license/{license}/{xyz.reversed=reversed/*}"
+    expected_uri = "abc/*/license/{license_}/{xyz.reversed_=reversed/*}"
+    assert utils.convert_uri_fieldnames(uri) == expected_uri
+
+
+def test_convert_uri_fieldname_no_fields():
+    uri = "abc/license"
+    assert utils.convert_uri_fieldnames(uri) == uri
+
+
+def test_convert_uri_fieldname_no_reserved_names():
+    uri = "abc/*/books/{book}/{xyz.chapter=page/*}"
+    assert utils.convert_uri_fieldnames(uri) == uri