diff --git a/.github/renovate.json5 b/.github/renovate.json5
index fc954c845..7bca69ac2 100644
--- a/.github/renovate.json5
+++ b/.github/renovate.json5
@@ -21,8 +21,6 @@
   },
 
   ignoreDeps: [
-    // axe-core starting v4.5 causes some axe-storybook tests to time out, ticket: EDS-779
-    'axe-core',
     // headlessui starting v1.7.6 causes some downstream feature tests to fail
     '@headlessui/react',
   ],
diff --git a/.storybook/pages/AlongDemo/AlongDemo.stories.ts b/.storybook/pages/AlongDemo/AlongDemo.stories.ts
index fa3e8477a..f540f0d01 100644
--- a/.storybook/pages/AlongDemo/AlongDemo.stories.ts
+++ b/.storybook/pages/AlongDemo/AlongDemo.stories.ts
@@ -19,4 +19,11 @@ export const WatchPage: StoryObj<Args> = {
     const nextPageButton = await canvas.findByText('Hogwarts');
     userEvent.click(nextPageButton);
   },
+  parameters: {
+    axe: {
+      // Don't run axe on this story. The video seems to cause asset preloading to fail (even when
+      // the video has preload="none").
+      skip: true,
+    },
+  },
 };
diff --git a/package.json b/package.json
index 6f61ebe32..c4d385a51 100644
--- a/package.json
+++ b/package.json
@@ -127,7 +127,7 @@
     "@types/react-beautiful-dnd": "^13.1.3",
     "@types/react-dom": "^18.0.11",
     "@types/react-portal": "^4.0.4",
-    "axe-core": "4.4.3",
+    "axe-core": "4.6.3",
     "chromatic": "^6.17.0",
     "codecov": "^3.8.3",
     "copyfiles": "^2.4.1",
diff --git a/yarn.lock b/yarn.lock
index d8f46b089..9334c42ec 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -1674,7 +1674,7 @@ __metadata:
     "@types/react-beautiful-dnd": ^13.1.3
     "@types/react-dom": ^18.0.11
     "@types/react-portal": ^4.0.4
-    axe-core: 4.4.3
+    axe-core: 4.6.3
     chromatic: ^6.17.0
     clsx: ^1.2.1
     codecov: ^3.8.3
@@ -6357,14 +6357,7 @@ __metadata:
   languageName: node
   linkType: hard
 
-"axe-core@npm:4.4.3":
-  version: 4.4.3
-  resolution: "axe-core@npm:4.4.3"
-  checksum: c3ea000d9ace3ba0bc747c8feafc24b0de62a0f7d93021d0f77b19c73fca15341843510f6170da563d51535d6cfb7a46c5fc0ea36170549dbb44b170208450a2
-  languageName: node
-  linkType: hard
-
-"axe-core@npm:^4.2.0, axe-core@npm:^4.6.2":
+"axe-core@npm:4.6.3, axe-core@npm:^4.2.0, axe-core@npm:^4.6.2":
   version: 4.6.3
   resolution: "axe-core@npm:4.6.3"
   checksum: d0c46be92b9707c48b88a53cd5f471b155a2bfc8bf6beffb514ecd14e30b4863e340b5fc4f496d82a3c562048088c1f3ff5b93b9b3b026cb9c3bfacfd535da10