diff --git a/packages/react/src/components/Tooltip/Tooltip.js b/packages/react/src/components/Tooltip/Tooltip.js
index 5da2568febbf..5a22adb2e107 100644
--- a/packages/react/src/components/Tooltip/Tooltip.js
+++ b/packages/react/src/components/Tooltip/Tooltip.js
@@ -303,6 +303,7 @@ class Tooltip extends Component {
     this._hasContextMenu = evt.type === 'contextmenu';
     if (state === 'click') {
       evt.stopPropagation();
+      evt.preventDefault();
       const shouldOpen = this.isControlled
         ? !this.props.open
         : !this.state.open;
@@ -338,6 +339,7 @@ class Tooltip extends Component {
 
     if (keyDownMatch(event, [keys.Enter, keys.Space])) {
       event.stopPropagation();
+      event.preventDefault();
       const shouldOpen = this.isControlled
         ? !this.props.open
         : !this.state.open;