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@@ -21,9 +21,9 @@ I'm also the Metadata Workgroup Lead for the Knight Data Governance Committee, w
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* Probabilistic graphical models
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## Selected Projects
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**Project: Using Signatures of Replication Stress to Prioritize Combination Therapies**
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**Team: Mills Lab**
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**Role: Project Lead**
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**Project: Using Signatures of Replication Stress to Prioritize Combination Therapies**<br/>
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**Team: Mills Lab**<br/>
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**Role: Project Lead**<br/>
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* Responsible for project design and execution; mining for markers and signatures of replication stress in RNAseq and proteomics data across cell lines, syngeneic mouse models, and patient biopsies; includes mining public patient cohorts and internal Mills Lab datasets
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* Assess concordance of existing signatures/ marker sets and integrate into candidate consensus signature
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* Identify and prioritize drugs for pairing with DNA damage repair inhibitors to target replication stress deficiencies

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