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Retention scores systematically underestimated #28

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kbseah opened this issue Aug 26, 2021 · 0 comments
Open

Retention scores systematically underestimated #28

kbseah opened this issue Aug 26, 2021 · 0 comments

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@kbseah
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kbseah commented Aug 26, 2021

Both MILRET and MILRAA count only reads that completely span an IES and either contain an insert or do not. If inserts/IESs are too long, the mapping will have a clip instead of an insert. For short IESs this is negligible, but as IESs are longer, a greater proportion of mapped IES+ reads will have clips, but these are currently ignored in calculating the retention score.

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