diff --git a/pkg/services/ngalert/api/api_alertmanager_guards.go b/pkg/services/ngalert/api/api_alertmanager_guards.go
index 1b1f7b438d67..90b6dd922546 100644
--- a/pkg/services/ngalert/api/api_alertmanager_guards.go
+++ b/pkg/services/ngalert/api/api_alertmanager_guards.go
@@ -3,6 +3,7 @@ package api
 import (
 	"encoding/json"
 	"fmt"
+	"time"
 
 	"github.com/google/go-cmp/cmp"
 	"github.com/google/go-cmp/cmp/cmpopts"
@@ -137,7 +138,14 @@ func checkMuteTimes(currentConfig apimodels.GettableUserConfig, newConfig apimod
 			return fmt.Errorf("cannot delete provisioned mute time '%s'", muteTime.Name)
 		}
 		reporter := cmputil.DiffReporter{}
-		options := []cmp.Option{cmp.Reporter(&reporter), cmpopts.EquateEmpty()}
+		options := []cmp.Option{
+			cmp.Reporter(&reporter),
+			cmp.Comparer(func(a, b *time.Location) bool {
+				// Check if both are nil or both have the same string representation
+				return (a == nil && b == nil) || (a != nil && b != nil && a.String() == b.String())
+			}),
+			cmpopts.EquateEmpty(),
+		}
 		timesEqual := cmp.Equal(muteTime.TimeIntervals, postedMT.TimeIntervals, options...)
 		if !timesEqual {
 			return fmt.Errorf("cannot save provisioned mute time '%s'", muteTime.Name)
diff --git a/pkg/services/ngalert/api/api_alertmanager_guards_test.go b/pkg/services/ngalert/api/api_alertmanager_guards_test.go
index d0219ed02f02..93f0d8dcf630 100644
--- a/pkg/services/ngalert/api/api_alertmanager_guards_test.go
+++ b/pkg/services/ngalert/api/api_alertmanager_guards_test.go
@@ -2,6 +2,7 @@ package api
 
 import (
 	"testing"
+	"time"
 
 	amConfig "github.com/prometheus/alertmanager/config"
 	"github.com/prometheus/alertmanager/pkg/labels"
@@ -563,6 +564,7 @@ func defaultInterval(t *testing.T) []timeinterval.TimeInterval {
 	t.Helper()
 	return []timeinterval.TimeInterval{
 		{
+			Location: &timeinterval.Location{Location: time.Local},
 			Years: []timeinterval.YearRange{
 				{
 					InclusiveRange: timeinterval.InclusiveRange{